Relaxing parametric assumptions for non-linear Mendelian randomization using a doubly-ranked stratification method

• Haodong Tian ,

  Roles Conceptualization, Formal analysis, Methodology, Software, Writing – original draft, Writing – review & editing

  * E-mail: haodong.tian@mrc-bsu.cam.ac.uk

  Affiliation MRC Biostatistics Unit, School of Clinical Medicine, University of Cambridge, Cambridge, United Kingdom

  https://orcid.org/0000-0002-2859-5398

  ⨯
• Amy M. Mason,

  Roles Software, Validation, Writing – review & editing

  Affiliation British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom

  ⨯
• Cunhao Liu,

  Roles Validation, Writing – review & editing

  Affiliation MRC Biostatistics Unit, School of Clinical Medicine, University of Cambridge, Cambridge, United Kingdom

  ⨯
• Stephen Burgess

  Roles Conceptualization, Formal analysis, Project administration, Supervision, Writing – original draft, Writing – review & editing

  Affiliations MRC Biostatistics Unit, School of Clinical Medicine, University of Cambridge, Cambridge, United Kingdom, British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom

  ⨯