Integrated analysis of genome-wide association studies and 3D epigenomic characteristics reveal the BMP2 gene regulating loin muscle depth in Yorkshire pigs

Yuanxin Miao; Yunxia Zhao; Siqi Wan; Quanshun Mei; Heng Wang; Chuanke Fu; Xinyun Li; Shuhong Zhao; Xuewen Xu; Tao Xiang

doi:10.1371/journal.pgen.1010820

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Peer-reviewed

Research Article

Integrated analysis of genome-wide association studies and 3D epigenomic characteristics reveal the BMP2 gene regulating loin muscle depth in Yorkshire pigs

Yuanxin Miao ,

Contributed equally to this work with: Yuanxin Miao, Yunxia Zhao, Siqi Wan

Roles Conceptualization, Formal analysis, Funding acquisition, Software, Writing – original draft

Affiliations Key Laboratory of Agricultural Animal Genetics, Breeding and Reproduction of Ministry of Education & Key Laboratory of Swine Genetics and Breeding of Ministry of Agriculture, Huazhong Agricultural University, Wuhan 430070, China, Research Institute of Agricultural Biotechnology, Jingchu University of Technology, Jingmen 448000, China
⨯
Yunxia Zhao ,

Contributed equally to this work with: Yuanxin Miao, Yunxia Zhao, Siqi Wan

Roles Conceptualization, Formal analysis, Methodology, Writing – original draft

Affiliation Key Laboratory of Agricultural Animal Genetics, Breeding and Reproduction of Ministry of Education & Key Laboratory of Swine Genetics and Breeding of Ministry of Agriculture, Huazhong Agricultural University, Wuhan 430070, China
⨯
Siqi Wan ,

Contributed equally to this work with: Yuanxin Miao, Yunxia Zhao, Siqi Wan

Roles Formal analysis, Software, Writing – original draft

Affiliation Key Laboratory of Agricultural Animal Genetics, Breeding and Reproduction of Ministry of Education & Key Laboratory of Swine Genetics and Breeding of Ministry of Agriculture, Huazhong Agricultural University, Wuhan 430070, China
⨯
Quanshun Mei,

Roles Software

Affiliation Key Laboratory of Agricultural Animal Genetics, Breeding and Reproduction of Ministry of Education & Key Laboratory of Swine Genetics and Breeding of Ministry of Agriculture, Huazhong Agricultural University, Wuhan 430070, China
⨯
Heng Wang,

Roles Writing – review & editing

Affiliation Key Laboratory of Agricultural Animal Genetics, Breeding and Reproduction of Ministry of Education & Key Laboratory of Swine Genetics and Breeding of Ministry of Agriculture, Huazhong Agricultural University, Wuhan 430070, China
⨯
Chuanke Fu,

Roles Software

Affiliation Key Laboratory of Agricultural Animal Genetics, Breeding and Reproduction of Ministry of Education & Key Laboratory of Swine Genetics and Breeding of Ministry of Agriculture, Huazhong Agricultural University, Wuhan 430070, China
⨯
Xinyun Li,

Roles Writing – review & editing

Affiliations Key Laboratory of Agricultural Animal Genetics, Breeding and Reproduction of Ministry of Education & Key Laboratory of Swine Genetics and Breeding of Ministry of Agriculture, Huazhong Agricultural University, Wuhan 430070, China, Hubei Hongshan laboratory, Huazhong Agricultural University, Wuhan 430070, China
⨯
Shuhong Zhao,

Roles Funding acquisition, Writing – review & editing

Affiliations Key Laboratory of Agricultural Animal Genetics, Breeding and Reproduction of Ministry of Education & Key Laboratory of Swine Genetics and Breeding of Ministry of Agriculture, Huazhong Agricultural University, Wuhan 430070, China, Hubei Hongshan laboratory, Huazhong Agricultural University, Wuhan 430070, China
⨯
Xuewen Xu ,

Roles Methodology, Writing – review & editing

* E-mail: Xuewen_Xu@mail.hzau.edu.cn (XX); Tao.Xiang@mail.hzau.edu.cn (TX)

Affiliation Key Laboratory of Agricultural Animal Genetics, Breeding and Reproduction of Ministry of Education & Key Laboratory of Swine Genetics and Breeding of Ministry of Agriculture, Huazhong Agricultural University, Wuhan 430070, China
⨯
Tao Xiang

Roles Conceptualization, Funding acquisition, Methodology, Writing – original draft

* E-mail: Xuewen_Xu@mail.hzau.edu.cn (XX); Tao.Xiang@mail.hzau.edu.cn (TX)

Affiliation Key Laboratory of Agricultural Animal Genetics, Breeding and Reproduction of Ministry of Education & Key Laboratory of Swine Genetics and Breeding of Ministry of Agriculture, Huazhong Agricultural University, Wuhan 430070, China

https://orcid.org/0000-0001-6134-2627

⨯

Integrated analysis of genome-wide association studies and 3D epigenomic characteristics reveal the BMP2 gene regulating loin muscle depth in Yorkshire pigs

Yuanxin Miao,
Yunxia Zhao,
Siqi Wan,
Quanshun Mei,
Heng Wang,
Chuanke Fu,
Xinyun Li,
Shuhong Zhao,
Xuewen Xu,
Tao Xiang

Published: June 20, 2023
https://doi.org/10.1371/journal.pgen.1010820

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