Regularized sequence-context mutational trees capture variation in mutation rates across the human genome

• Christopher J. Adams,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Software, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Genomics and Computational Biology Graduate Group, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

  https://orcid.org/0000-0002-8615-9164

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• Mitchell Conery,

  Roles Data curation, Visualization, Writing – review & editing

  Affiliation Genomics and Computational Biology Graduate Group, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

  https://orcid.org/0000-0001-7640-0797

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• Benjamin J. Auerbach,

  Roles Formal analysis, Writing – review & editing

  Affiliation Genomics and Computational Biology Graduate Group, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

  https://orcid.org/0000-0003-0496-1119

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• Shane T. Jensen,

  Roles Conceptualization, Writing – review & editing

  Affiliation Department of Statistics and Data Science, The Wharton School at the University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

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• Iain Mathieson,

  Roles Conceptualization, Writing – review & editing

  Affiliation Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

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• Benjamin F. Voight

  Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: bvoight@upenn.edu

  Affiliations Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America, Department of Systems Pharmacology and Translational Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America, Institute for Translational Medicine and Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

  https://orcid.org/0000-0002-6205-9994

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