Heterozygous inversion breakpoints suppress meiotic crossovers by altering recombination repair outcomes

• Haosheng Li,

  Roles Investigation

  Affiliation Department of Biology, Case Western Reserve University, Cleveland, Ohio, United States of America

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• Erica Berent,

  Roles Investigation

  Affiliation Department of Biology, Case Western Reserve University, Cleveland, Ohio, United States of America

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• Savannah Hadjipanteli,

  Roles Investigation

  Current address: Department of Biology & Biochemistry, University of Houston, Houston, Texas, United States of America

  Affiliation Department of Biology, Case Western Reserve University, Cleveland, Ohio, United States of America

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• Miranda Galey,

  Roles Investigation

  Affiliations Division of Genetic Medicine, Department of Pediatrics, University of Washington and Seattle Children’s Hospital, Seattle, Washington, United States of America, Department of Laboratory Medicine and Pathology, University of Washington, Seattle, Washington, United States of America

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• Nigel Muhammad-Lahbabi,

  Roles Formal analysis

  Affiliation Department of Biology, Case Western Reserve University, Cleveland, Ohio, United States of America

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• Danny E. Miller,

  Roles Formal analysis, Writing – review & editing

  Affiliations Division of Genetic Medicine, Department of Pediatrics, University of Washington and Seattle Children’s Hospital, Seattle, Washington, United States of America, Department of Laboratory Medicine and Pathology, University of Washington, Seattle, Washington, United States of America, Brotman Baty Institute for Precision Medicine, University of Washington, Seattle, Washington, United States of America

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• K. Nicole Crown

  Roles Conceptualization, Investigation, Writing – original draft, Writing – review & editing

  * E-mail: knc38@case.edu

  Affiliation Department of Biology, Case Western Reserve University, Cleveland, Ohio, United States of America

  https://orcid.org/0000-0002-2595-3428

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