Pharmacological vitamin C inhibits mTOR signaling and tumor growth by degrading Rictor and inducing HMOX1 expression

• Senlin Qin ,

  Contributed equally to this work with: Senlin Qin, Guoyan Wang

  Roles Conceptualization, Investigation, Methodology, Writing – original draft

  Affiliation College of Animal Science and Technology, Northwest A&F University, Yangling, Shaanxi, China

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• Guoyan Wang ,

  Contributed equally to this work with: Senlin Qin, Guoyan Wang

  Roles Conceptualization, Investigation, Methodology, Writing – original draft

  Affiliation College of Animal Science and Technology, Northwest A&F University, Yangling, Shaanxi, China

  ⨯
• Lei Chen,

  Roles Funding acquisition, Investigation, Project administration, Resources, Supervision

  Affiliation College of Animal Science and Technology, Northwest A&F University, Yangling, Shaanxi, China

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• Huijun Geng,

  Roles Investigation, Methodology

  Affiliation College of Animal Science and Technology, Northwest A&F University, Yangling, Shaanxi, China

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• Yining Zheng,

  Roles Investigation

  Affiliation College of Animal Science and Technology, Northwest A&F University, Yangling, Shaanxi, China

  ⨯
• Chao Xia,

  Roles Investigation

  Affiliation College of Animal Science and Technology, Northwest A&F University, Yangling, Shaanxi, China

  ⨯
• Shengru Wu,

  Roles Writing – review & editing

  Affiliation College of Animal Science and Technology, Northwest A&F University, Yangling, Shaanxi, China

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• Junhu Yao ,

  Roles Funding acquisition, Project administration, Resources, Supervision, Writing – review & editing

  * E-mail: yaojunhu2008@nwafu.edu.cn (J.Y); denglu128128@nwafu.edu.cn (L.D)

  Affiliation College of Animal Science and Technology, Northwest A&F University, Yangling, Shaanxi, China

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• Lu Deng

  Roles Conceptualization, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: yaojunhu2008@nwafu.edu.cn (J.Y); denglu128128@nwafu.edu.cn (L.D)

  Affiliation College of Animal Science and Technology, Northwest A&F University, Yangling, Shaanxi, China

  https://orcid.org/0000-0002-3744-4102

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