Genome-wide association study identifies four pan-ancestry loci for suicidal ideation in the Million Veteran Program

• Allison E. Ashley-Koch ,

  Contributed equally to this work with: Allison E. Ashley-Koch, Nathan A. Kimbrel

  Roles Conceptualization, Funding acquisition, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: Allison.ashleykoch@duke.edu

  Affiliations Duke Molecular Physiology Institute, Durham, North Carolina, United States of America, Department of Medicine, Duke University Health System, Durham, North Carolina, United States of America

  https://orcid.org/0000-0001-5409-9155

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• Nathan A. Kimbrel ,

  Contributed equally to this work with: Allison E. Ashley-Koch, Nathan A. Kimbrel

  Roles Conceptualization, Funding acquisition, Writing – original draft, Writing – review & editing

  Affiliations Durham Veterans Affairs (VA) Health Care System, Durham, North Carolina, United States of America, VA Mid-Atlantic Mental Illness Research, Education and Clinical Center, Durham, North Carolina, United States of America, VA Health Services Research and Development Center of Innovation to Accelerate Discovery and Practice Transformation, Durham, North Carolina, United States of America, Department of Psychiatry and Behavioral Sciences, Duke University School of Medicine, Durham, North Carolina, United States of America

  https://orcid.org/0000-0001-7218-1005

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• Xue J. Qin,

  Roles Formal analysis, Visualization, Writing – review & editing

  Affiliations Duke Molecular Physiology Institute, Durham, North Carolina, United States of America, Durham Veterans Affairs (VA) Health Care System, Durham, North Carolina, United States of America

  https://orcid.org/0000-0001-9169-253X

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• Jennifer H. Lindquist,

  Roles Formal analysis, Writing – review & editing

  Affiliation VA Health Services Research and Development Center of Innovation to Accelerate Discovery and Practice Transformation, Durham, North Carolina, United States of America

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• Melanie E. Garrett,

  Roles Formal analysis, Writing – review & editing

  Affiliation Duke Molecular Physiology Institute, Durham, North Carolina, United States of America

  https://orcid.org/0000-0003-2302-6150

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• Michelle F. Dennis,

  Roles Funding acquisition, Project administration, Writing – review & editing

  Affiliations Durham Veterans Affairs (VA) Health Care System, Durham, North Carolina, United States of America, Department of Psychiatry and Behavioral Sciences, Duke University School of Medicine, Durham, North Carolina, United States of America

  https://orcid.org/0000-0003-0734-7448

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• Lauren P. Hair,

  Roles Project administration, Writing – review & editing

  Affiliations Durham Veterans Affairs (VA) Health Care System, Durham, North Carolina, United States of America, Department of Psychiatry and Behavioral Sciences, Duke University School of Medicine, Durham, North Carolina, United States of America

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• Jennifer E. Huffman,

  Roles Data curation, Project administration, Writing – review & editing

  Affiliation Massachusetts Veterans Epidemiology Research and Information Center (MAVERIC), VA Boston Healthcare System, Boston, Massachusetts, United States of America

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• Daniel A. Jacobson,

  Roles Writing – review & editing

  Affiliations Biosciences, Oak Ridge National Laboratory, Oak Ridge, TN, United States of America, Bredesen Center for Interdisciplinary Research and Graduate Education, University of Tennessee Knoxville, Knoxville, Tennessee, United States of America, Department of Psychology, NeuroNet Research Center, University of Tennessee Knoxville, Knoxville, Tennessee, United States of America

  https://orcid.org/0000-0002-9822-8251

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• Ravi K. Madduri,

  Roles Data curation, Resources, Writing – review & editing

  Affiliations Consortium for Advanced Science and Engineering, The University of Chicago, Chicago, Illinois, United States of America, Data Science and Learning Division, Argonne National Laboratory, Lemont, Illinois, United States of America

  https://orcid.org/0000-0003-2130-2887

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• Hilary Coon,

  Roles Validation, Writing – review & editing

  Affiliations Department of Psychiatry, Huntsman Mental Health Institute, University of Utah School of Medicine, Salt Lake City, Utah, United States of America, Biomedical Informatics, University of Utah School of Medicine, Salt Lake City, Utah, United States of America

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• Anna R. Docherty,

  Roles Validation, Writing – review & editing

  Affiliations Department of Psychiatry, Huntsman Mental Health Institute, University of Utah School of Medicine, Salt Lake City, Utah, United States of America, Department of Psychiatry, Virginia Commonwealth University, Richmond, Virginia, United States of America

  https://orcid.org/0000-0001-7139-7007

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• Jooeun Kang,

  Roles Validation, Writing – review & editing

  Affiliation Division of Genetic Medicine, Department of Medicine, Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America

  https://orcid.org/0000-0002-6603-0988

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• Niamh Mullins,

  Roles Validation, Writing – review & editing

  Affiliations Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America, Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America

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• Douglas M. Ruderfer,

  Roles Validation, Writing – review & editing

  Affiliations Division of Genetic Medicine, Department of Medicine, Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America, Department of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America, Department of Psychiatry and Behavioral Sciences, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America

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• the VA Million Veteran Program (MVP) ,

  ¶Membership of the VA Million Veteran Program (MVP) is provided in Supporting Information file S2 Text. Membership of the MVP Suicide Exemplar Workgroup is provided in Supporting Information file S3 Text. Membership of the International Suicide Genetics Consortium is provided in Supporting Information file S4 Text.

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• the MVP Suicide Exemplar Workgroup ,

  ¶Membership of the VA Million Veteran Program (MVP) is provided in Supporting Information file S2 Text. Membership of the MVP Suicide Exemplar Workgroup is provided in Supporting Information file S3 Text. Membership of the International Suicide Genetics Consortium is provided in Supporting Information file S4 Text.

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• the International Suicide Genetics Consortium ,

  ¶Membership of the VA Million Veteran Program (MVP) is provided in Supporting Information file S2 Text. Membership of the MVP Suicide Exemplar Workgroup is provided in Supporting Information file S3 Text. Membership of the International Suicide Genetics Consortium is provided in Supporting Information file S4 Text.

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• Philip D. Harvey,

  Roles Writing – review & editing

  Affiliations Research Service Bruce W. Carter VA Medical Center, Miami, Florida, United States of America, Department of Psychiatry and Behavioral Sciences, University of Miami Miller School of Medicine, Miami, Florida, United States of America

  https://orcid.org/0000-0002-9501-9366

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• Benjamin H. McMahon,

  Roles Funding acquisition, Project administration, Writing – review & editing

  Affiliation Theoretical Biology and Biophysics, Los Alamos National Laboratory, Los Alamos, New Mexico, United States of America

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• David W. Oslin,

  Roles Funding acquisition, Writing – review & editing

  Affiliations VISN 4 Mental Illness Research, Education, and Clinical Center, Center of Excellence, Corporal Michael J. Crescenz VA Medical Center, Philadelphia, Pennsylvania, United States of America, Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Pennsylvania, United States of America

  https://orcid.org/0000-0003-4392-4599

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• Elizabeth R. Hauser,

  Roles Funding acquisition, Supervision, Writing – review & editing

  Affiliations Duke Molecular Physiology Institute, Durham, North Carolina, United States of America, Durham Veterans Affairs (VA) Health Care System, Durham, North Carolina, United States of America, Department of Biostatistics and Bioinformatics, Duke University School of Medicine, Durham, North Carolina, United States of America

  https://orcid.org/0000-0003-0367-9189

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• Michael A. Hauser,

  Roles Funding acquisition, Writing – review & editing

  Affiliation Duke Molecular Physiology Institute, Durham, North Carolina, United States of America

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•  [ ... ],
• Jean C. Beckham

  Roles Funding acquisition, Project administration, Writing – review & editing

  Affiliations Durham Veterans Affairs (VA) Health Care System, Durham, North Carolina, United States of America, VA Mid-Atlantic Mental Illness Research, Education and Clinical Center, Durham, North Carolina, United States of America, Department of Psychiatry and Behavioral Sciences, Duke University School of Medicine, Durham, North Carolina, United States of America

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