The MOV10 RNA helicase is a dosage-dependent host restriction factor for LINE1 retrotransposition in mice

• Yongjuan Guan,

  Roles Conceptualization, Formal analysis, Investigation, Methodology, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliations Department of Biomedical Sciences, University of Pennsylvania School of Veterinary Medicine, Philadelphia, Pennsylvania, United States of America, College of Life Sciences, Capital Normal University, Beijing, China

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• Hongyan Gao,

  Roles Data curation, Formal analysis

  Affiliation Center for Infectious Disease Research, School of Medicine, Tsinghua University, Beijing, China

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• N. Adrian Leu,

  Roles Methodology

  Affiliation Department of Biomedical Sciences, University of Pennsylvania School of Veterinary Medicine, Philadelphia, Pennsylvania, United States of America

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• Anastassios Vourekas,

  Roles Formal analysis, Investigation, Methodology, Writing – review & editing

  Affiliations Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America, Department of Biological Sciences, Louisiana State University, Baton Rouge, Louisiana, United States of America

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• Panagiotis Alexiou,

  Roles Formal analysis

  Affiliation Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

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• Manolis Maragkakis,

  Roles Formal analysis

  Affiliation Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

  https://orcid.org/0000-0002-3158-1763

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• Zhenlong Kang,

  Roles Investigation

  Affiliations Department of Biomedical Sciences, University of Pennsylvania School of Veterinary Medicine, Philadelphia, Pennsylvania, United States of America, State Key Laboratory of Reproductive Medicine, Nanjing Medical University, Nanjing, China

  https://orcid.org/0000-0003-3729-6514

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• Zissimos Mourelatos,

  Roles Formal analysis, Funding acquisition, Writing – review & editing

  Affiliation Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

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• Guanxiang Liang,

  Roles Formal analysis, Writing – review & editing

  Affiliation Center for Infectious Disease Research, School of Medicine, Tsinghua University, Beijing, China

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• P. Jeremy Wang

  Roles Conceptualization, Formal analysis, Funding acquisition, Resources, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: pwang@vet.upenn.edu

  Affiliation Department of Biomedical Sciences, University of Pennsylvania School of Veterinary Medicine, Philadelphia, Pennsylvania, United States of America

  https://orcid.org/0000-0003-2311-4089

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