Escape from X-inactivation in twins exhibits intra- and inter-individual variability across tissues and is heritable

• Antonino Zito ,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Software, Writing – original draft, Writing – review & editing

  * E-mail: antonino.zito@kcl.ac.uk (AZ); kerrin.small@kcl.ac.uk (KSS)

  Current address: Department of Molecular Biology, Massachusetts General Hospital, Boston, Massachusetts, United States of America; Department of Genetics, The Blavatnik Institute, Harvard Medical School, Boston, Massachusetts, United States of America

  Affiliation Department of Twin Research & Genetic Epidemiology, King’s College London, London, United Kingdom

  https://orcid.org/0000-0003-1931-984X

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• Amy L. Roberts ,

  Contributed equally to this work with: Amy L. Roberts, Alessia Visconti

  Roles Formal analysis, Investigation, Writing – original draft, Writing – review & editing

  Affiliation Department of Twin Research & Genetic Epidemiology, King’s College London, London, United Kingdom

  https://orcid.org/0000-0002-5704-9249

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• Alessia Visconti ,

  Contributed equally to this work with: Amy L. Roberts, Alessia Visconti

  Roles Formal analysis, Investigation, Writing – original draft

  Affiliation Department of Twin Research & Genetic Epidemiology, King’s College London, London, United Kingdom

  https://orcid.org/0000-0003-4144-2019

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• Niccolo’ Rossi,

  Roles Formal analysis, Investigation

  Affiliation Department of Twin Research & Genetic Epidemiology, King’s College London, London, United Kingdom

  https://orcid.org/0000-0002-8285-7627

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• Rosa Andres-Ejarque,

  Roles Resources

  Affiliation St John’s Institute of Dermatology, Faculty of Life Science & Medicine, King’s College London, London, United Kingdom

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• Stefano Nardone,

  Roles Investigation, Resources, Visualization

  Affiliation Division of Endocrinology, Diabetes, and Metabolism, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, United States of America

  https://orcid.org/0000-0002-9317-4784

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• Julia S. El-Sayed Moustafa,

  Roles Writing – original draft

  Affiliation Department of Twin Research & Genetic Epidemiology, King’s College London, London, United Kingdom

  https://orcid.org/0000-0001-6963-6654

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• Mario Falchi,

  Roles Formal analysis, Resources

  Affiliation Department of Twin Research & Genetic Epidemiology, King’s College London, London, United Kingdom

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• Kerrin S. Small

  Roles Conceptualization, Methodology, Project administration, Resources, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: antonino.zito@kcl.ac.uk (AZ); kerrin.small@kcl.ac.uk (KSS)

  Affiliation Department of Twin Research & Genetic Epidemiology, King’s College London, London, United Kingdom

  https://orcid.org/0000-0003-4566-0005

  ⨯