A flexible empirical Bayes approach to multivariate multiple regression, and its improved accuracy in predicting multi-tissue gene expression from genotypes

• Fabio Morgante ,

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Software, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: fabiom@clemson.edu (FM); mstephens@uchicago.edu (MS)

  Affiliations Center for Human Genetics, Clemson University, Greenwood, South Carolina, United States of America, Department of Genetics and Biochemistry, Clemson University, Clemson, South Carolina, United States of America, Section of Genetic Medicine, Department of Medicine, University of Chicago, Chicago, Illinois, United States of America

  https://orcid.org/0000-0003-3285-1988

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• Peter Carbonetto,

  Roles Investigation, Methodology, Resources, Software, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliations Department of Human Genetics, University of Chicago, Chicago, Illinois, United States of America, Research Computing Center, University of Chicago, Chicago, Illinois, United States of America

  https://orcid.org/0000-0003-1144-6780

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• Gao Wang,

  Roles Data curation, Formal analysis, Resources, Software, Writing – original draft, Writing – review & editing

  Affiliations Department of Human Genetics, University of Chicago, Chicago, Illinois, United States of America, Department of Neurology, Columbia University, New York, New York, United States of America, Gertrude H. Sergievsky Center, Columbia University, New York, New York, United States of America

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• Yuxin Zou,

  Roles Data curation, Methodology, Software, Writing – review & editing

  Affiliations Department of Statistics, University of Chicago, Chicago, Illinois, United States of America, Regeneron Genetics Center, Regeneron Pharmaceuticals Inc., Tarrytown, New York, United States of America

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• Abhishek Sarkar,

  Roles Methodology, Software, Writing – original draft, Writing – review & editing

  Current address: Vesalius Therapeutics, Inc., Cambridge, Massachusetts, United States of America

  Affiliation Department of Human Genetics, University of Chicago, Chicago, Illinois, United States of America

  https://orcid.org/0000-0002-4636-9255

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• Matthew Stephens

  Roles Conceptualization, Funding acquisition, Methodology, Project administration, Resources, Supervision, Validation, Writing – original draft, Writing – review & editing

  * E-mail: fabiom@clemson.edu (FM); mstephens@uchicago.edu (MS)

  Affiliations Department of Human Genetics, University of Chicago, Chicago, Illinois, United States of America, Department of Statistics, University of Chicago, Chicago, Illinois, United States of America

  https://orcid.org/0000-0001-5397-9257

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