A toolbox for class I HDACs reveals isoform specific roles in gene regulation and protein acetylation

• Lena Hess ,

  Contributed equally to this work with: Lena Hess, Verena Moos

  Roles Conceptualization, Investigation, Methodology, Validation, Visualization, Writing – original draft

  Affiliation Center for Anatomy and Cell Biology, Medical University of Vienna, Vienna, Austria

  ⨯
• Verena Moos ,

  Contributed equally to this work with: Lena Hess, Verena Moos

  Roles Conceptualization, Investigation, Methodology, Validation, Visualization

  Affiliation Center for Anatomy and Cell Biology, Medical University of Vienna, Vienna, Austria

  https://orcid.org/0000-0002-7578-8176

  ⨯
• Arnel A. Lauber,

  Roles Formal analysis, Investigation, Methodology

  Affiliation Center for Anatomy and Cell Biology, Medical University of Vienna, Vienna, Austria

  https://orcid.org/0000-0002-2949-728X

  ⨯
• Wolfgang Reiter,

  Roles Data curation, Formal analysis, Investigation, Methodology, Validation, Visualization

  Affiliations Mass Spectrometry Core Facility, Max Perutz Labs, Vienna BioCenter, Vienna, Austria, Department of Biochemistry and Cell Biology, Max Perutz Labs, University of Vienna, Vienna BioCenter, Vienna, Austria

  https://orcid.org/0000-0003-1266-8975

  ⨯
• Michael Schuster,

  Roles Data curation, Formal analysis, Software

  Affiliation CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria

  ⨯
• Natascha Hartl,

  Roles Investigation, Validation

  Affiliation Mass Spectrometry Core Facility, Max Perutz Labs, Vienna BioCenter, Vienna, Austria

  ⨯
• Daniel Lackner †,

  † Deceased.

  Roles Investigation, Methodology

  Affiliation Horizon Genomics, Vienna, Austria

  ⨯
• Thorina Boenke,

  Roles Investigation

  Affiliation CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria

  ⨯
• Anna Koren,

  Roles Investigation

  Affiliation CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria

  https://orcid.org/0000-0003-2528-4970

  ⨯
• Paloma M. Guzzardo,

  Roles Investigation, Methodology

  Affiliation Horizon Genomics, Vienna, Austria

  ⨯
• Brigitte Gundacker,

  Roles Investigation

  Affiliation Center for Anatomy and Cell Biology, Medical University of Vienna, Vienna, Austria

  ⨯
• Anna Riegler,

  Roles Investigation

  Affiliation Center for Anatomy and Cell Biology, Medical University of Vienna, Vienna, Austria

  ⨯
• Petra Vician,

  Roles Investigation

  Affiliation Center for Anatomy and Cell Biology, Medical University of Vienna, Vienna, Austria

  ⨯
• Claudia Miccolo,

  Roles Investigation

  Affiliation Department of Experimental Oncology, IEO, European Institute of Oncology IRCCS, Milan, Italy

  ⨯
• Susanna Leiter,

  Roles Investigation

  Affiliation Center for Anatomy and Cell Biology, Medical University of Vienna, Vienna, Austria

  ⨯
• Mahesh B. Chandrasekharan,

  Roles Investigation

  Affiliation Department of Radiation Oncology and Huntsman Cancer Institute, University of Utah School of Medicine, Salt Lake City, Utah, United States of America

  https://orcid.org/0000-0002-9956-8354

  ⨯
• Terezia Vcelkova,

  Roles Investigation, Validation

  Affiliation Center for Anatomy and Cell Biology, Medical University of Vienna, Vienna, Austria

  ⨯
• Andrea Tanzer,

  Roles Visualization

  Affiliation Center for Anatomy and Cell Biology, Medical University of Vienna, Vienna, Austria

  https://orcid.org/0000-0003-2873-4236

  ⨯
• Jun Qi Jun,

  Roles Resources

  Affiliation Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America

  ⨯
• James Bradner,

  Roles Resources

  Affiliation Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America

  ⨯
• Gerald Brosch,

  Roles Resources

  Affiliation Institute of Molecular Biology, Innsbruck Medical University, Innsbruck, Austria

  ⨯
• Markus Hartl,

  Roles Data curation, Formal analysis, Investigation, Methodology, Software, Validation

  Affiliations Mass Spectrometry Core Facility, Max Perutz Labs, Vienna BioCenter, Vienna, Austria, Department of Biochemistry and Cell Biology, Max Perutz Labs, University of Vienna, Vienna BioCenter, Vienna, Austria

  https://orcid.org/0000-0002-4970-7336

  ⨯
• Christoph Bock,

  Roles Conceptualization

  Affiliations CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria, Institute of Artificial Intelligence, Center for Medical Statistics, Informatics, and Intelligent Systems, Medical University of Vienna, Vienna, Austria

  ⨯
• Tilmann Bürckstümmer,

  Roles Conceptualization, Funding acquisition, Methodology

  Affiliation Horizon Genomics, Vienna, Austria

  ⨯
• Stefan Kubicek,

  Roles Conceptualization, Formal analysis, Validation

  Affiliation CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria

  https://orcid.org/0000-0003-0855-8343

  ⨯
• Susanna Chiocca,

  Roles Conceptualization, Funding acquisition

  Affiliation Department of Experimental Oncology, IEO, European Institute of Oncology IRCCS, Milan, Italy

  https://orcid.org/0000-0002-9721-0850

  ⨯
• Srividya Bhaskara,

  Roles Conceptualization, Supervision

  Affiliation Department of Radiation Oncology and Huntsman Cancer Institute, University of Utah School of Medicine, Salt Lake City, Utah, United States of America

  ⨯
•  [ ... ],
• Christian Seiser

  Roles Conceptualization, Funding acquisition, Project administration, Supervision, Writing – original draft

  * E-mail: christian.seiser@meduniwien.ac.at

  Affiliation Center for Anatomy and Cell Biology, Medical University of Vienna, Vienna, Austria

  https://orcid.org/0000-0002-7046-9352

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