Network assisted analysis of de novo variants using protein-protein interaction information identified 46 candidate genes for congenital heart disease

• Yuhan Xie,

  Roles Conceptualization, Data curation, Formal analysis, Methodology, Project administration, Software, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Department of Biostatistics, Yale School of Public Health, New Haven, Connecticut, United States of America

  https://orcid.org/0000-0002-1738-0885

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• Wei Jiang,

  Roles Conceptualization, Methodology, Supervision, Writing – original draft, Writing – review & editing

  Affiliation Department of Biostatistics, Yale School of Public Health, New Haven, Connecticut, United States of America

  https://orcid.org/0000-0001-6120-5278

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• Weilai Dong,

  Roles Resources, Validation, Writing – original draft, Writing – review & editing

  Affiliation Department of Genetics, Yale School of Medicine, New Haven, Connecticut, United States of America

  https://orcid.org/0000-0002-8376-1758

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• Hongyu Li,

  Roles Data curation, Methodology, Writing – review & editing

  Affiliation Department of Biostatistics, Yale School of Public Health, New Haven, Connecticut, United States of America

  https://orcid.org/0000-0001-6525-9310

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• Sheng Chih Jin,

  Roles Resources, Validation, Writing – review & editing

  Affiliation Department of Genetics, Washington University School of Medicine, St Louis, Missouri, United States of America

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• Martina Brueckner,

  Roles Resources, Validation, Writing – review & editing

  Affiliations Department of Genetics, Yale School of Medicine, New Haven, Connecticut, United States of America, Department of Pediatrics, Yale University, New Haven, Connecticut, United States of America

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• Hongyu Zhao

  Roles Funding acquisition, Investigation, Project administration, Resources, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: hongyu.zhao@yale.edu

  Affiliations Department of Biostatistics, Yale School of Public Health, New Haven, Connecticut, United States of America, Department of Genetics, Yale School of Medicine, New Haven, Connecticut, United States of America, Program in Computational Biology and Bioinformatics, Yale University, New Haven, Connecticut, United States of America

  https://orcid.org/0000-0003-1195-9607

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