Testing non-autonomous antimalarial gene drive effectors using self-eliminating drivers in the African mosquito vector Anopheles gambiae

David A. Ellis; George Avraam; Astrid Hoermann; Claudia A. S. Wyer; Yi Xin Ong; George K. Christophides; Nikolai Windbichler

doi:10.1371/journal.pgen.1010244

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Peer-reviewed

Research Article

Testing non-autonomous antimalarial gene drive effectors using self-eliminating drivers in the African mosquito vector Anopheles gambiae

David A. Ellis,

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Visualization, Writing – original draft, Writing – review & editing

Current address: Ear Institute, University College London, London, United Kingdom; Francis Crick Institute, London, United Kingdom

Affiliation Department of Life Sciences, Imperial College London, London, United Kingdom

https://orcid.org/0000-0002-3366-7712

⨯
George Avraam,

Roles Investigation, Methodology

Affiliation Department of Life Sciences, Imperial College London, London, United Kingdom

https://orcid.org/0000-0002-5489-2003

⨯
Astrid Hoermann,

Roles Investigation, Resources

Affiliation Department of Life Sciences, Imperial College London, London, United Kingdom

https://orcid.org/0000-0002-1346-5945

⨯
Claudia A. S. Wyer,

Roles Investigation

Current address: Department of Life Sciences, Imperial College London, Silwood Park, Ascot, United Kingdom

Affiliation Department of Life Sciences, Imperial College London, London, United Kingdom

https://orcid.org/0000-0003-0449-8507

⨯
Yi Xin Ong,

Roles Investigation

Affiliation Department of Life Sciences, Imperial College London, London, United Kingdom

https://orcid.org/0000-0002-3134-2236

⨯
George K. Christophides,

Roles Conceptualization, Funding acquisition, Project administration, Resources, Writing – review & editing

Affiliation Department of Life Sciences, Imperial College London, London, United Kingdom

https://orcid.org/0000-0002-3323-1687

⨯
Nikolai Windbichler

Roles Conceptualization, Formal analysis, Funding acquisition, Methodology, Project administration, Resources, Software, Supervision, Visualization, Writing – original draft, Writing – review & editing

* E-mail: nikolai.windbichler@imperial.ac.uk

Affiliation Department of Life Sciences, Imperial College London, London, United Kingdom

https://orcid.org/0000-0001-9896-1165

⨯

Testing non-autonomous antimalarial gene drive effectors using self-eliminating drivers in the African mosquito vector Anopheles gambiae

David A. Ellis,
George Avraam,
Astrid Hoermann,
Claudia A. S. Wyer,
Yi Xin Ong,
George K. Christophides,
Nikolai Windbichler

Published: June 2, 2022
https://doi.org/10.1371/journal.pgen.1010244

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