An in vivo drug repurposing screen and transcriptional analyses reveals the serotonin pathway and GSK3 as major therapeutic targets for NGLY1 deficiency

• Kevin A. Hope,

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Department of Human Genetics, University of Utah School of Medicine, Salt Lake City, Utah, United States of America

  https://orcid.org/0000-0002-5722-5070

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• Alexys R. Berman,

  Roles Investigation

  Affiliation Department of Human Genetics, University of Utah School of Medicine, Salt Lake City, Utah, United States of America

  https://orcid.org/0000-0002-8377-7426

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• Randall T. Peterson,

  Roles Conceptualization, Funding acquisition, Resources, Supervision, Writing – review & editing

  Affiliation College of Pharmacy, University of Utah, Salt Lake City, Utah, United States of America

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• Clement Y. Chow

  Roles Conceptualization, Funding acquisition, Methodology, Project administration, Resources, Supervision, Writing – review & editing

  * E-mail: cchow@genetics.utah.edu

  Affiliation Department of Human Genetics, University of Utah School of Medicine, Salt Lake City, Utah, United States of America

  https://orcid.org/0000-0002-3104-7923

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