Regulation of Mus81-Eme1 structure-specific endonuclease by Eme1 SUMO-binding and Rad3ATR kinase is essential in the absence of Rqh1BLM helicase

Cédric Giaccherini; Sarah Scaglione; Stéphane Coulon; Pierre-Marie Dehé; Pierre-Henri L. Gaillard

doi:10.1371/journal.pgen.1010165

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Peer-reviewed

Research Article

Regulation of Mus81-Eme1 structure-specific endonuclease by Eme1 SUMO-binding and Rad3^ATR kinase is essential in the absence of Rqh1^BLM helicase

Cédric Giaccherini ,

Contributed equally to this work with: Cédric Giaccherini, Pierre-Marie Dehé

Roles Conceptualization, Formal analysis, Investigation, Methodology, Validation, Visualization, Writing – review & editing

Affiliation Centre de Recherche en Cancérologie de Marseille, CRCM, Inserm, CNRS, Aix-Marseille Université, Institut Paoli-Calmettes, Marseille, France

https://orcid.org/0000-0002-3602-814X

⨯
Sarah Scaglione,

Roles Formal analysis, Investigation, Methodology, Validation, Visualization, Writing – review & editing

Affiliation Centre de Recherche en Cancérologie de Marseille, CRCM, Inserm, CNRS, Aix-Marseille Université, Institut Paoli-Calmettes, Marseille, France

https://orcid.org/0000-0001-6705-5645

⨯
Stéphane Coulon,

Roles Formal analysis, Investigation, Writing – review & editing

Affiliation Centre de Recherche en Cancérologie de Marseille, CRCM, Inserm, CNRS, Aix-Marseille Université, Institut Paoli-Calmettes, Marseille, France

https://orcid.org/0000-0001-8090-914X

⨯
Pierre-Marie Dehé ,

Contributed equally to this work with: Cédric Giaccherini, Pierre-Marie Dehé

Roles Conceptualization, Formal analysis, Investigation, Methodology, Project administration, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

* E-mail: pierre-marie.dehe@inserm.fr (P-MD); pierre-henri.gaillard@inserm.fr (P-HLG)

Affiliation Centre de Recherche en Cancérologie de Marseille, CRCM, Inserm, CNRS, Aix-Marseille Université, Institut Paoli-Calmettes, Marseille, France

https://orcid.org/0000-0003-1558-6983

⨯
Pierre-Henri L. Gaillard

Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Project administration, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

* E-mail: pierre-marie.dehe@inserm.fr (P-MD); pierre-henri.gaillard@inserm.fr (P-HLG)

Affiliation Centre de Recherche en Cancérologie de Marseille, CRCM, Inserm, CNRS, Aix-Marseille Université, Institut Paoli-Calmettes, Marseille, France

https://orcid.org/0000-0003-0781-0826

⨯

Regulation of Mus81-Eme1 structure-specific endonuclease by Eme1 SUMO-binding and Rad3^ATR kinase is essential in the absence of Rqh1^BLM helicase

Cédric Giaccherini,
Sarah Scaglione,
Stéphane Coulon,
Pierre-Marie Dehé,
Pierre-Henri L. Gaillard

Published: April 22, 2022
https://doi.org/10.1371/journal.pgen.1010165
See the preprint

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