HiCuT: An efficient and low input method to identify protein-directed chromatin interactions

Satish Sati; Parker Jones; Hali S. Kim; Linda A. Zhou; Emmanuel Rapp-Reyes; Thomas H. Leung

doi:10.1371/journal.pgen.1010121

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Open Access

Peer-reviewed

Research Article

HiCuT: An efficient and low input method to identify protein-directed chromatin interactions

Satish Sati,

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Software, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

Affiliation Department of Dermatology, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

https://orcid.org/0000-0001-8236-9466

⨯
Parker Jones ,

Contributed equally to this work with: Parker Jones, Hali S. Kim

Roles Data curation, Investigation, Validation, Visualization, Writing – original draft, Writing – review & editing

Affiliation Department of Dermatology, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
⨯
Hali S. Kim ,

Contributed equally to this work with: Parker Jones, Hali S. Kim

Roles Data curation, Validation, Visualization, Writing – original draft

Affiliation Department of Dermatology, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
⨯
Linda A. Zhou,

Roles Data curation, Formal analysis, Software

Affiliation Department of Genetics, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
⨯
Emmanuel Rapp-Reyes,

Roles Data curation

Affiliation Department of Dermatology, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

https://orcid.org/0000-0002-5752-1291

⨯
Thomas H. Leung

Roles Conceptualization, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

* E-mail: thl@pennmedicine.upenn.edu

Affiliations Department of Dermatology, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America, Corporal Michael J. Crescenz Department of Veterans Affairs Medical Center, Philadelphia, Pennsylvania, United States of America

https://orcid.org/0000-0003-1086-0824

⨯

HiCuT: An efficient and low input method to identify protein-directed chromatin interactions

Satish Sati,
Parker Jones,
Hali S. Kim,
Linda A. Zhou,
Emmanuel Rapp-Reyes,
Thomas H. Leung

Published: March 23, 2022
https://doi.org/10.1371/journal.pgen.1010121

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Chromatin
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Protein interactions
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ChIA PET
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Single nucleotide polymorphisms
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Keratinocytes
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