Activation of the ubiquitin-proteasome system contributes to oculopharyngeal muscular dystrophy through muscle atrophy

Cécile Ribot; Cédric Soler; Aymeric Chartier; Sandy Al Hayek; Rima Naït-Saïdi; Nicolas Barbezier; Olivier Coux; Martine Simonelig

doi:10.1371/journal.pgen.1010015

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Open Access

Peer-reviewed

Research Article

Activation of the ubiquitin-proteasome system contributes to oculopharyngeal muscular dystrophy through muscle atrophy

Cécile Ribot ,

Contributed equally to this work with: Cécile Ribot, Cédric Soler, Aymeric Chartier

Roles Formal analysis, Writing – original draft

Affiliation mRNA Regulation and Development, Institute of Human Genetics, UMR9002 CNRS-Univ Montpellier, Montpellier, France
⨯
Cédric Soler ,

Contributed equally to this work with: Cécile Ribot, Cédric Soler, Aymeric Chartier

Roles Formal analysis

Current address: GReD Laboratory, Clermont-Auvergne University, INSERM U1103, CNRS UMR6293, Clermont-Ferrand, France

Affiliation mRNA Regulation and Development, Institute of Human Genetics, UMR9002 CNRS-Univ Montpellier, Montpellier, France

https://orcid.org/0000-0002-2312-5370

⨯
Aymeric Chartier ,

Contributed equally to this work with: Cécile Ribot, Cédric Soler, Aymeric Chartier

Roles Data curation, Formal analysis

Affiliation mRNA Regulation and Development, Institute of Human Genetics, UMR9002 CNRS-Univ Montpellier, Montpellier, France
⨯
Sandy Al Hayek,

Roles Data curation

Affiliation GReD Laboratory, Clermont-Auvergne University, INSERM U1103, CNRS UMR6293, Clermont-Ferrand, France

https://orcid.org/0000-0003-4623-9626

⨯
Rima Naït-Saïdi,

Roles Data curation

Affiliation mRNA Regulation and Development, Institute of Human Genetics, UMR9002 CNRS-Univ Montpellier, Montpellier, France
⨯
Nicolas Barbezier,

Roles Formal analysis

Affiliation mRNA Regulation and Development, Institute of Human Genetics, UMR9002 CNRS-Univ Montpellier, Montpellier, France

https://orcid.org/0000-0003-2940-9881

⨯
Olivier Coux,

Roles Formal analysis, Supervision

Affiliation Ubiquitin-proteasome system and cell cycle control, Montpellier Cell Biology Research Center, UMR5237 CNRS-Univ Montpellier, Montpellier, France
⨯
Martine Simonelig

Roles Conceptualization, Funding acquisition, Supervision, Writing – original draft, Writing – review & editing

* E-mail: Martine.Simonelig@igh.cnrs.fr

Affiliation mRNA Regulation and Development, Institute of Human Genetics, UMR9002 CNRS-Univ Montpellier, Montpellier, France

https://orcid.org/0000-0002-3731-6979

⨯

Activation of the ubiquitin-proteasome system contributes to oculopharyngeal muscular dystrophy through muscle atrophy

Cécile Ribot,
Cédric Soler,
Aymeric Chartier,
Sandy Al Hayek,
Rima Naït-Saïdi,
Nicolas Barbezier,
Olivier Coux,
Martine Simonelig

Published: January 13, 2022
https://doi.org/10.1371/journal.pgen.1010015

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Muscle proteins
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Drosophila melanogaster
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