Epigenetic and transcriptional dysregulation in CD4+ T cells in patients with atopic dermatitis

• Amy A. Eapen ,

  Contributed equally to this work with: Amy A. Eapen, Sreeja Parameswaran

  Roles Conceptualization, Investigation, Project administration, Writing – original draft, Writing – review & editing

  Affiliations Division of Allergy and Immunology, Cincinnati Children’s Hospital Medical Center, Cincinnati, Ohio, United States of America, Division of Allergy and Clinical Immunology, Henry Ford Health System, Detroit, Michigan, United States of America, Center for Autoimmune Genomics and Etiology, Cincinnati Children’s Hospital Medical Center, Cincinnati, Ohio, United States of America

  https://orcid.org/0000-0003-1629-1511

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• Sreeja Parameswaran ,

  Contributed equally to this work with: Amy A. Eapen, Sreeja Parameswaran

  Roles Data curation, Formal analysis, Investigation, Software, Visualization

  Affiliation Center for Autoimmune Genomics and Etiology, Cincinnati Children’s Hospital Medical Center, Cincinnati, Ohio, United States of America

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• Carmy Forney,

  Roles Investigation, Methodology, Writing – review & editing

  Affiliation Center for Autoimmune Genomics and Etiology, Cincinnati Children’s Hospital Medical Center, Cincinnati, Ohio, United States of America

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• Lee E. Edsall,

  Roles Data curation, Formal analysis, Investigation, Writing – review & editing

  Affiliation Center for Autoimmune Genomics and Etiology, Cincinnati Children’s Hospital Medical Center, Cincinnati, Ohio, United States of America

  https://orcid.org/0000-0002-0326-2829

  ⨯
• Daniel Miller,

  Roles Investigation, Writing – review & editing

  Affiliation Center for Autoimmune Genomics and Etiology, Cincinnati Children’s Hospital Medical Center, Cincinnati, Ohio, United States of America

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• Omer Donmez,

  Roles Data curation, Investigation, Methodology, Writing – review & editing

  Affiliation Center for Autoimmune Genomics and Etiology, Cincinnati Children’s Hospital Medical Center, Cincinnati, Ohio, United States of America

  https://orcid.org/0000-0002-9720-4039

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• Katelyn Dunn,

  Roles Investigation, Writing – review & editing

  Affiliation Center for Autoimmune Genomics and Etiology, Cincinnati Children’s Hospital Medical Center, Cincinnati, Ohio, United States of America

  ⨯
• Xiaoming Lu,

  Roles Data curation, Formal analysis, Writing – review & editing

  Affiliation Center for Autoimmune Genomics and Etiology, Cincinnati Children’s Hospital Medical Center, Cincinnati, Ohio, United States of America

  https://orcid.org/0000-0002-0830-2826

  ⨯
• Marissa Granitto,

  Roles Data curation, Formal analysis, Writing – review & editing

  Affiliation Center for Autoimmune Genomics and Etiology, Cincinnati Children’s Hospital Medical Center, Cincinnati, Ohio, United States of America

  https://orcid.org/0000-0002-1758-9881

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• Hope Rowden,

  Roles Investigation, Writing – review & editing

  Affiliation Center for Autoimmune Genomics and Etiology, Cincinnati Children’s Hospital Medical Center, Cincinnati, Ohio, United States of America

  https://orcid.org/0000-0002-6186-7287

  ⨯
• Adam Z. Magier,

  Roles Investigation, Writing – review & editing

  Affiliation Division of Allergy and Immunology, Cincinnati Children’s Hospital Medical Center, Cincinnati, Ohio, United States of America

  https://orcid.org/0000-0003-4469-4692

  ⨯
• Mario Pujato,

  Roles Investigation, Software, Writing – review & editing

  Affiliation Center for Autoimmune Genomics and Etiology, Cincinnati Children’s Hospital Medical Center, Cincinnati, Ohio, United States of America

  https://orcid.org/0000-0002-2415-3111

  ⨯
• Xiaoting Chen,

  Roles Formal analysis, Investigation, Methodology, Software, Writing – review & editing

  Affiliation Center for Autoimmune Genomics and Etiology, Cincinnati Children’s Hospital Medical Center, Cincinnati, Ohio, United States of America

  https://orcid.org/0000-0002-3782-3962

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• Kenneth Kaufman,

  Roles Formal analysis, Writing – review & editing

  Affiliations Center for Autoimmune Genomics and Etiology, Cincinnati Children’s Hospital Medical Center, Cincinnati, Ohio, United States of America, Divisions of Biomedical Informatics and Developmental Biology, Cincinnati Children’s Hospital Medical Center, Cincinnati, Ohio, United States of America, Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio, United States of America, Cincinnati Veterans Administration, Cincinnati, Ohio, United States of America

  https://orcid.org/0000-0001-8195-1876

  ⨯
• David I. Bernstein,

  Roles Investigation, Resources, Writing – review & editing

  Affiliation Division of Immunology, Allergy, and Rheumatology, University of Cincinnati, College of Medicine, Cincinnati, Ohio, United States of America

  https://orcid.org/0000-0003-1466-8418

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• Ashley L. Devonshire,

  Roles Conceptualization, Investigation, Writing – original draft, Writing – review & editing

  Affiliations Division of Allergy and Immunology, Cincinnati Children’s Hospital Medical Center, Cincinnati, Ohio, United States of America, Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio, United States of America

  https://orcid.org/0000-0002-6341-5794

  ⨯
• Marc E. Rothenberg,

  Roles Funding acquisition, Resources, Writing – original draft, Writing – review & editing

  Affiliations Division of Allergy and Immunology, Cincinnati Children’s Hospital Medical Center, Cincinnati, Ohio, United States of America, Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio, United States of America

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• Matthew T. Weirauch ,

  Roles Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Resources, Software, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: Matthew.Weirauch@cchmc.org (MTW); Leah.Kottyan@cchmc.org (LCK)

  Affiliations Center for Autoimmune Genomics and Etiology, Cincinnati Children’s Hospital Medical Center, Cincinnati, Ohio, United States of America, Divisions of Biomedical Informatics and Developmental Biology, Cincinnati Children’s Hospital Medical Center, Cincinnati, Ohio, United States of America, Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio, United States of America

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•  [ ... ],
• Leah C. Kottyan

  Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: Matthew.Weirauch@cchmc.org (MTW); Leah.Kottyan@cchmc.org (LCK)

  Affiliations Division of Allergy and Immunology, Cincinnati Children’s Hospital Medical Center, Cincinnati, Ohio, United States of America, Center for Autoimmune Genomics and Etiology, Cincinnati Children’s Hospital Medical Center, Cincinnati, Ohio, United States of America, Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio, United States of America

  https://orcid.org/0000-0003-3979-2220

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