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Open Access
Peer-reviewed
Research Article
RB depletion is required for the continuous growth of tumors initiated by loss of RB
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Alex Doan ,
Contributed equally to this work with: Alex Doan, Julia Arand
Roles Conceptualization, Formal analysis, Investigation, Visualization, Writing – original draft
Affiliations Department of Pediatrics, Stanford University, Stanford, California, United States of America, Department of Genetics, Stanford University, Stanford, California, United States of America
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Julia Arand ,
Contributed equally to this work with: Alex Doan, Julia Arand
Roles Conceptualization, Formal analysis, Investigation, Supervision, Visualization, Writing – original draft
Affiliations Department of Pediatrics, Stanford University, Stanford, California, United States of America, Department of Genetics, Stanford University, Stanford, California, United States of America, Center of Anatomy and Cell Biology, Department of Cell and Developmental Biology, Medical University of Vienna, Vienna, Austria
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Diana Gong,
Roles Formal analysis, Writing – review & editing
Affiliations Department of Pediatrics, Stanford University, Stanford, California, United States of America, Department of Genetics, Stanford University, Stanford, California, United States of America, Department of Bioengineering, Stanford University, Stanford, California, United States of America
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Alexandros P. Drainas,
Roles Formal analysis, Writing – review & editing
Affiliations Department of Pediatrics, Stanford University, Stanford, California, United States of America, Department of Genetics, Stanford University, Stanford, California, United States of America
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Yan Ting Shue,
Roles Formal analysis, Writing – review & editing
Affiliations Department of Pediatrics, Stanford University, Stanford, California, United States of America, Department of Genetics, Stanford University, Stanford, California, United States of America
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Myung Chang Lee,
Roles Formal analysis, Visualization, Writing – review & editing
Affiliations Department of Pediatrics, Stanford University, Stanford, California, United States of America, Department of Genetics, Stanford University, Stanford, California, United States of America
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Shuyuan Zhang,
Roles Investigation, Writing – review & editing
Affiliation Department of Biology, Stanford University, Stanford, California, United States of America
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David M. Walter,
Roles Investigation, Writing – review & editing
Affiliations Department of Cancer Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America, Abramson Family Cancer Research Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
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Andrea C. Chaikovsky,
Roles Validation, Writing – review & editing
Affiliations Department of Pediatrics, Stanford University, Stanford, California, United States of America, Department of Genetics, Stanford University, Stanford, California, United States of America
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David M. Feldser,
Roles Supervision, Writing – review & editing
Affiliations Department of Cancer Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America, Abramson Family Cancer Research Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
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Hannes Vogel,
Roles Formal analysis, Writing – review & editing
Affiliation Department of Pathology, Stanford University, Stanford, California, United States of America
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Lukas E. Dow,
Roles Resources, Writing – review & editing
Affiliations Sandra and Edward Meyer Cancer Center, Weill Cornell Medicine, New York, New York, United States of America, Department of Biochemistry, Weill Cornell Medicine, New York, New York, United States of America, Department of Medicine, Weill Cornell Medicine, New York, New York, United States of America
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Jan M. Skotheim,
Roles Supervision, Writing – review & editing
Affiliation Department of Biology, Stanford University, Stanford, California, United States of America
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Julien Sage
Roles Conceptualization, Funding acquisition, Project administration, Supervision, Visualization, Writing – original draft, Writing – review & editing
* E-mail: julsage@stanford.edu
Affiliations Department of Pediatrics, Stanford University, Stanford, California, United States of America, Department of Genetics, Stanford University, Stanford, California, United States of America
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RB depletion is required for the continuous growth of tumors initiated by loss of RB
- Alex Doan,
- Julia Arand,
- Diana Gong,
- Alexandros P. Drainas,
- Yan Ting Shue,
- Myung Chang Lee,
- Shuyuan Zhang,
- David M. Walter,
- Andrea C. Chaikovsky,
- David M. Feldser
- Published: December 8, 2021
- https://doi.org/10.1371/journal.pgen.1009941