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Open Access
Peer-reviewed
Research Article
Nucleoporin TPR promotes tRNA nuclear export and protein synthesis in lung cancer cells
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Miao Chen ,
Contributed equally to this work with: Miao Chen, Qian Long
Roles Conceptualization, Funding acquisition, Investigation, Methodology, Writing – original draft
* E-mail: chenmiao@sysucc.org.cn (MC); marc.gartenberg@rutgers.edu (MRG); dengwg@sysucc.org.cn (WD)
Affiliations State Key Laboratory of Oncology in South China and Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou, Guangdong, China, Department of Biochemistry and Molecular Biology, Robert Wood Johnson Medical School, Piscataway, New Jersey, United States of America
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Qian Long ,
Contributed equally to this work with: Miao Chen, Qian Long
Roles Investigation, Methodology
Affiliation State Key Laboratory of Oncology in South China and Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou, Guangdong, China
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Melinda S. Borrie,
Roles Data curation, Investigation, Methodology
Affiliation Department of Biochemistry and Molecular Biology, Robert Wood Johnson Medical School, Piscataway, New Jersey, United States of America
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Haohui Sun,
Roles Investigation
Affiliation State Key Laboratory of Oncology in South China and Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou, Guangdong, China
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Changlin Zhang,
Roles Investigation, Methodology
Affiliations State Key Laboratory of Oncology in South China and Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou, Guangdong, China, Department of Obstetrics and Gynecology, The Seventh Affiliated Hospital of Sun Yat-sen University, Shenzhen, Guangdong, China
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Han Yang,
Roles Data curation, Resources
Affiliation State Key Laboratory of Oncology in South China and Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou, Guangdong, China
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Dingbo Shi,
Roles Investigation
Affiliation State Key Laboratory of Oncology in South China and Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou, Guangdong, China
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Marc R. Gartenberg ,
Roles Conceptualization, Funding acquisition, Methodology, Writing – review & editing
* E-mail: chenmiao@sysucc.org.cn (MC); marc.gartenberg@rutgers.edu (MRG); dengwg@sysucc.org.cn (WD)
Affiliations Department of Biochemistry and Molecular Biology, Robert Wood Johnson Medical School, Piscataway, New Jersey, United States of America, The Cancer Institute of New Jersey, Rutgers University, New Brunswick, New Jersey, United States of America
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Wuguo Deng
Roles Conceptualization, Funding acquisition, Writing – review & editing
* E-mail: chenmiao@sysucc.org.cn (MC); marc.gartenberg@rutgers.edu (MRG); dengwg@sysucc.org.cn (WD)
Affiliation State Key Laboratory of Oncology in South China and Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou, Guangdong, China
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Nucleoporin TPR promotes tRNA nuclear export and protein synthesis in lung cancer cells
- Miao Chen,
- Qian Long,
- Melinda S. Borrie,
- Haohui Sun,
- Changlin Zhang,
- Han Yang,
- Dingbo Shi,
- Marc R. Gartenberg,
- Wuguo Deng
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- Published: November 18, 2021
- https://doi.org/10.1371/journal.pgen.1009899