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Deficiency of ASGR1 in pigs recapitulates reduced risk factor for cardiovascular disease in humans
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Baocai Xie ,
Contributed equally to this work with: Baocai Xie, Xiaochen Shi, Yan Li
Roles Conceptualization, Data curation, Writing – original draft
Affiliations Key Laboratory of Animal Genetics, Breeding and Reproduction of Shaanxi Province, College of Animal Science and Technology, Northwest A&F University, Yangling, Shaanxi, China, Institute of Animal Genetics and Breeding, College of Animal Science and Technology, Sichuan Agricultural University, Chengdu, Sichuan, China
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Xiaochen Shi ,
Contributed equally to this work with: Baocai Xie, Xiaochen Shi, Yan Li
Roles Conceptualization, Data curation, Validation
Affiliation Key Laboratory of Animal Genetics, Breeding and Reproduction of Shaanxi Province, College of Animal Science and Technology, Northwest A&F University, Yangling, Shaanxi, China
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Yan Li ,
Contributed equally to this work with: Baocai Xie, Xiaochen Shi, Yan Li
Roles Conceptualization, Data curation, Writing – original draft
Affiliation Institute of Animal Genetics and Breeding, College of Animal Science and Technology, Sichuan Agricultural University, Chengdu, Sichuan, China
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Bo Xia,
Roles Investigation
Affiliation Key Laboratory of Animal Genetics, Breeding and Reproduction of Shaanxi Province, College of Animal Science and Technology, Northwest A&F University, Yangling, Shaanxi, China
⨯ - Jia Zhou,
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Minjie Du,
Roles Data curation, Investigation
Affiliation Chengdu Clonorgan Biotechnology Co. LTD, Chengdu, Sichuan, China
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Xiangyang Xing,
Roles Formal analysis, Investigation
Affiliation Chengdu Clonorgan Biotechnology Co. LTD, Chengdu, Sichuan, China
⨯ - Liang Bai,
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Enqi Liu,
Roles Methodology
Affiliation Institute of Cardiovascular Sciences, Health Science Center, Xi’an Jiao Tong University, Xi’an, Shaanxi, China
⨯ - Fernando Alvarez,
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Long Jin,
Roles Resources
Affiliation Institute of Animal Genetics and Breeding, College of Animal Science and Technology, Sichuan Agricultural University, Chengdu, Sichuan, China
⨯ - Shaoping Deng,
- Grant A. Mitchell,
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Dengke Pan ,
Roles Conceptualization, Funding acquisition, Resources, Writing – review & editing
* E-mail: dkpan@clonorgan.com (DP); mingzhou.li@sicau.edu.cn (ML); wujiangwei@nwafu.edu.cn (JW)
Affiliation Clinical Immunology Translational Medicine Key Laboratory of Sichuan Province, Sichuan Academy of Medical Sciences & Sichuan Provincial People’s Hospital, Chengdu, Sichuan, China
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Mingzhou Li ,
Roles Conceptualization, Funding acquisition, Writing – original draft, Writing – review & editing
* E-mail: dkpan@clonorgan.com (DP); mingzhou.li@sicau.edu.cn (ML); wujiangwei@nwafu.edu.cn (JW)
Affiliation Institute of Animal Genetics and Breeding, College of Animal Science and Technology, Sichuan Agricultural University, Chengdu, Sichuan, China
⨯ - [ ... ],
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Jiangwei Wu
Roles Conceptualization, Funding acquisition, Writing – original draft, Writing – review & editing
* E-mail: dkpan@clonorgan.com (DP); mingzhou.li@sicau.edu.cn (ML); wujiangwei@nwafu.edu.cn (JW)
Affiliation Key Laboratory of Animal Genetics, Breeding and Reproduction of Shaanxi Province, College of Animal Science and Technology, Northwest A&F University, Yangling, Shaanxi, China
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https://orcid.org/0000-0003-0611-0131
Deficiency of ASGR1 in pigs recapitulates reduced risk factor for cardiovascular disease in humans
- Baocai Xie,
- Xiaochen Shi,
- Yan Li,
- Bo Xia,
- Jia Zhou,
- Minjie Du,
- Xiangyang Xing,
- Liang Bai,
- Enqi Liu,
- Fernando Alvarez
- Published: November 11, 2021
- https://doi.org/10.1371/journal.pgen.1009891