Do sex hormones confound or mediate the effect of chronotype on breast and prostate cancer? A Mendelian randomization study

• Bryony L. Hayes ,

  Roles Formal analysis, Investigation, Writing – original draft

  * E-mail: bryony.hayes@bristol.ac.uk

  Affiliations MRC Integrative Epidemiology Unit, University of Bristol, Bristol, United Kingdom, Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, United Kingdom

  https://orcid.org/0000-0001-6340-0966

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• Timothy Robinson,

  Roles Supervision, Writing – review & editing

  Affiliations Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, United Kingdom, Bristol Cancer Institute, University Hospitals Bristol and Weston NHS Foundation Trust, Bristol, United Kingdom

  https://orcid.org/0000-0003-0933-646X

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• Siddhartha Kar,

  Roles Methodology, Writing – review & editing

  Affiliations MRC Integrative Epidemiology Unit, University of Bristol, Bristol, United Kingdom, Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, United Kingdom

  https://orcid.org/0000-0002-2314-1426

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• Katherine S. Ruth,

  Roles Writing – review & editing

  Affiliation Genetics of Human Complex Traits, University of Exeter Medical School, University of Exeter, Exeter, United Kingdom

  https://orcid.org/0000-0003-4966-9170

  ⨯
• Konstantinos K. Tsilidis,

  Roles Writing – review & editing

  Affiliations Department of Epidemiology and Biostatistics, Imperial College London, London, United Kingdom, Department of Hygiene and Epidemiology, University of Ioannina School of Medicine, Ioannina, Greece

  https://orcid.org/0000-0002-8452-8472

  ⨯
• Timothy Frayling,

  Roles Writing – review & editing

  Affiliation Genetics of Human Complex Traits, University of Exeter Medical School, University of Exeter, Exeter, United Kingdom

  https://orcid.org/0000-0001-8362-2603

  ⨯
• Anna Murray,

  Roles Writing – review & editing

  Affiliation Genetics of Human Complex Traits, University of Exeter Medical School, University of Exeter, Exeter, United Kingdom

  https://orcid.org/0000-0002-2351-2522

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• Richard M. Martin,

  Roles Supervision, Writing – review & editing

  Affiliations MRC Integrative Epidemiology Unit, University of Bristol, Bristol, United Kingdom, Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, United Kingdom, NIHR Bristol Biomedical Research Centre, at University Hospitals Bristol and Weston NHS Foundation Trust and the University of Bristol, Bristol, United Kingdom

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• Deborah A. Lawlor,

  Roles Supervision, Writing – review & editing

  Affiliations MRC Integrative Epidemiology Unit, University of Bristol, Bristol, United Kingdom, Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, United Kingdom, NIHR Bristol Biomedical Research Centre, at University Hospitals Bristol and Weston NHS Foundation Trust and the University of Bristol, Bristol, United Kingdom

  https://orcid.org/0000-0002-6793-2262

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• Rebecca C. Richmond

  Roles Supervision, Writing – review & editing

  Affiliations MRC Integrative Epidemiology Unit, University of Bristol, Bristol, United Kingdom, Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, United Kingdom

  https://orcid.org/0000-0003-0574-5071

  ⨯