Massively parallel reporter assays discover de novo exonic splicing mutants in paralogs of Autism genes

• Christy L. Rhine ,

  Contributed equally to this work with: Christy L. Rhine, Christopher Neil, Jing Wang

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Writing – original draft, Writing – review & editing

  Affiliations Molecular Biology, Cell Biology and Biochemistry, Brown University, Providence, Rhode Island, United States of America, Autism & Developmental Medicine Institute, and Genomic Medicine Institute, Geisinger, Danville, Pennsylvania, United States of America

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• Christopher Neil ,

  Contributed equally to this work with: Christy L. Rhine, Christopher Neil, Jing Wang

  Roles Formal analysis, Investigation, Validation

  Affiliations Molecular Biology, Cell Biology and Biochemistry, Brown University, Providence, Rhode Island, United States of America, Autism & Developmental Medicine Institute, and Genomic Medicine Institute, Geisinger, Danville, Pennsylvania, United States of America, C enter for Computational Molecular Biology, Brown University, Providence, Rhode Island, United States of America

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• Jing Wang ,

  Contributed equally to this work with: Christy L. Rhine, Christopher Neil, Jing Wang

  Roles Formal analysis, Investigation

  Affiliations Autism & Developmental Medicine Institute, and Genomic Medicine Institute, Geisinger, Danville, Pennsylvania, United States of America, C enter for Computational Molecular Biology, Brown University, Providence, Rhode Island, United States of America

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• Samantha Maguire,

  Roles Investigation, Validation, Writing – review & editing

  Affiliation Molecular Biology, Cell Biology and Biochemistry, Brown University, Providence, Rhode Island, United States of America

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• Luke Buerer,

  Roles Formal analysis, Investigation

  Affiliation C enter for Computational Molecular Biology, Brown University, Providence, Rhode Island, United States of America

  https://orcid.org/0000-0003-1391-3370

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• Mitchell Salomon,

  Roles Data curation, Formal analysis, Investigation

  Affiliation Molecular Biology, Cell Biology and Biochemistry, Brown University, Providence, Rhode Island, United States of America

  https://orcid.org/0000-0002-5147-6653

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• Ijeoma C. Meremikwu,

  Roles Investigation, Validation

  Affiliation Molecular Biology, Cell Biology and Biochemistry, Brown University, Providence, Rhode Island, United States of America

  https://orcid.org/0000-0001-9704-3127

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• Juliana Kim,

  Roles Validation

  Affiliation Molecular Biology, Cell Biology and Biochemistry, Brown University, Providence, Rhode Island, United States of America

  https://orcid.org/0000-0003-0763-4279

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• Natasha T. Strande,

  Roles Data curation, Investigation, Writing – review & editing

  Affiliation Autism & Developmental Medicine Institute, and Genomic Medicine Institute, Geisinger, Danville, Pennsylvania, United States of America

  https://orcid.org/0000-0001-5148-9772

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• William G. Fairbrother

  Roles Conceptualization, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: william_fairbrother@brown.edu

  Affiliations Molecular Biology, Cell Biology and Biochemistry, Brown University, Providence, Rhode Island, United States of America, C enter for Computational Molecular Biology, Brown University, Providence, Rhode Island, United States of America, Hassenfeld Child Health Innovation Institute of Brown University, Providence, Rhode Island, United States of America

  https://orcid.org/0000-0003-2694-4934

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