A novel AST2 mutation generated upon whole-genome transformation of Saccharomyces cerevisiae confers high tolerance to 5-Hydroxymethylfurfural (HMF) and other inhibitors

• Gert Vanmarcke,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Writing – original draft, Writing – review & editing

  Affiliations Laboratory of Molecular Cell Biology, Institute of Botany and Microbiology, KU Leuven, Leuven-Heverlee, Belgium, Center for Microbiology, VIB, Leuven-Heverlee, Belgium

  https://orcid.org/0000-0001-5468-5007

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• Quinten Deparis,

  Roles Data curation, Formal analysis, Methodology, Software

  Affiliations Laboratory of Molecular Cell Biology, Institute of Botany and Microbiology, KU Leuven, Leuven-Heverlee, Belgium, Center for Microbiology, VIB, Leuven-Heverlee, Belgium

  https://orcid.org/0000-0003-4995-4369

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• Ward Vanthienen,

  Roles Formal analysis, Investigation

  Affiliations Laboratory of Molecular Cell Biology, Institute of Botany and Microbiology, KU Leuven, Leuven-Heverlee, Belgium, Center for Microbiology, VIB, Leuven-Heverlee, Belgium

  https://orcid.org/0000-0002-4634-8702

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• Arne Peetermans,

  Roles Formal analysis, Investigation

  Affiliations Laboratory of Molecular Cell Biology, Institute of Botany and Microbiology, KU Leuven, Leuven-Heverlee, Belgium, Center for Microbiology, VIB, Leuven-Heverlee, Belgium

  https://orcid.org/0000-0002-9678-5046

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• Maria R. Foulquié-Moreno ,

  Roles Conceptualization, Formal analysis, Project administration, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: mrfoulquiem@gmail.com (MRF-M); johan.thevelein@novelyeast.com (JMT)

  Affiliations Laboratory of Molecular Cell Biology, Institute of Botany and Microbiology, KU Leuven, Leuven-Heverlee, Belgium, Center for Microbiology, VIB, Leuven-Heverlee, Belgium

  https://orcid.org/0000-0003-2931-3273

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• Johan M. Thevelein

  Roles Conceptualization, Funding acquisition, Project administration, Resources, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: mrfoulquiem@gmail.com (MRF-M); johan.thevelein@novelyeast.com (JMT)

  Affiliations Laboratory of Molecular Cell Biology, Institute of Botany and Microbiology, KU Leuven, Leuven-Heverlee, Belgium, Center for Microbiology, VIB, Leuven-Heverlee, Belgium, NovelYeast bv, Open Bio-Incubator, Erasmus High School, Brussels (Jette), Belgium

  https://orcid.org/0000-0002-2626-0180

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