Translational repression of NMD targets by GIGYF2 and EIF4E2

Boris Zinshteyn; Niladri K. Sinha; Syed Usman Enam; Benjamin Koleske; Rachel Green

doi:10.1371/journal.pgen.1009813

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Open Access

Peer-reviewed

Research Article

Translational repression of NMD targets by GIGYF2 and EIF4E2

Boris Zinshteyn,

Roles Conceptualization, Funding acquisition, Investigation, Writing – original draft, Writing – review & editing

Current address: Panorama Medicine, Philadelphia, Pennsylvania, United States of America

Affiliations Department of Molecular Biology and Genetics, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America, Howard Hughes Medical Institute, Chevy Chase, Maryland, United States of America

https://orcid.org/0000-0003-0103-3501

⨯
Niladri K. Sinha,

Roles Investigation, Methodology, Writing – review & editing

Affiliations Department of Molecular Biology and Genetics, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America, Howard Hughes Medical Institute, Chevy Chase, Maryland, United States of America

https://orcid.org/0000-0002-9143-495X

⨯
Syed Usman Enam,

Roles Investigation

Current address: Department of Genetics, Stanford University School of Medicine, Stanford, California, United States of America

Affiliations Department of Molecular Biology and Genetics, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America, Howard Hughes Medical Institute, Chevy Chase, Maryland, United States of America

https://orcid.org/0000-0001-8976-0660

⨯
Benjamin Koleske,

Roles Investigation

Affiliations Department of Molecular Biology and Genetics, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America, Howard Hughes Medical Institute, Chevy Chase, Maryland, United States of America

https://orcid.org/0000-0002-1479-218X

⨯
Rachel Green

Roles Funding acquisition, Supervision, Writing – review & editing

* E-mail: ragreen@jhmi.edu

Affiliations Department of Molecular Biology and Genetics, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America, Howard Hughes Medical Institute, Chevy Chase, Maryland, United States of America

https://orcid.org/0000-0001-9337-2003

⨯

Translational repression of NMD targets by GIGYF2 and EIF4E2

Boris Zinshteyn,
Niladri K. Sinha,
Syed Usman Enam,
Benjamin Koleske,
Rachel Green

Published: October 19, 2021
https://doi.org/10.1371/journal.pgen.1009813

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Ribosomes
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Messenger RNA
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Untranslated regions
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Flow cytometry
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CRISPRs
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Introns
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Protein translation
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RNA sequencing
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