Transcriptional progression during meiotic prophase I reveals sex-specific features and X chromosome dynamics in human fetal female germline

• Xueying Fan ,

  Contributed equally to this work with: Xueying Fan, Ioannis Moustakas, Vanessa Torrens-Juaneda

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Software, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Department of Anatomy and Embryology, Leiden University Medical Center, Leiden, The Netherlands

  https://orcid.org/0000-0002-7809-2254

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• Ioannis Moustakas ,

  Contributed equally to this work with: Xueying Fan, Ioannis Moustakas, Vanessa Torrens-Juaneda

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Software, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliations Department of Anatomy and Embryology, Leiden University Medical Center, Leiden, The Netherlands, Sequencing Analysis Support Core, Department of Biomedical Data Sciences, Leiden University Medical Center, Leiden, The Netherlands

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• Vanessa Torrens-Juaneda ,

  Contributed equally to this work with: Xueying Fan, Ioannis Moustakas, Vanessa Torrens-Juaneda

  Roles Conceptualization, Formal analysis, Investigation, Methodology, Project administration, Software, Writing – original draft, Writing – review & editing

  Affiliation Department of Anatomy and Embryology, Leiden University Medical Center, Leiden, The Netherlands

  https://orcid.org/0000-0003-0965-947X

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• Qijing Lei,

  Roles Methodology, Validation, Writing – review & editing

  Affiliation Center for Reproductive Medicine, Reproductive Biology Laboratory, Amsterdam Reproduction and Development Research Institute, Amsterdam University Medical Centers, Location AMC, Amsterdam, the Netherlands

  https://orcid.org/0000-0002-4959-1345

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• Geert Hamer,

  Roles Methodology, Validation, Writing – review & editing

  Affiliation Center for Reproductive Medicine, Reproductive Biology Laboratory, Amsterdam Reproduction and Development Research Institute, Amsterdam University Medical Centers, Location AMC, Amsterdam, the Netherlands

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• Leoni A. Louwe,

  Roles Resources, Writing – review & editing

  Affiliation Department of Gynaecology, Leiden University Medical Center, Leiden, The Netherlands

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• Gonneke S. K. Pilgram,

  Roles Resources, Writing – review & editing

  Affiliation Department of Gynaecology, Leiden University Medical Center, Leiden, The Netherlands

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• Karoly Szuhai,

  Roles Methodology, Writing – review & editing

  Affiliation Department of Cell and Chemical Biology, Leiden University Medical Center, Leiden, The Netherlands

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• Roberto Matorras,

  Roles Resources, Writing – review & editing

  Affiliation IVIRMA, IVI Bilbao, Bilbao, Spain; Human Reproduction Unit, Cruces University Hospital, Bilbao, Spain; Department of Obstetrics and Gynecology, Basque Country University, Spain; Biocruces Bizkaia Health Research Institute, Bilbao, Spain

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• Cristina Eguizabal,

  Roles Resources, Writing – review & editing

  Affiliations Cell Therapy, Stem Cells and Tissues Group, Basque Centre for Blood Transfusion and Human Tissues, Galdakao, Spain, Biocruces Bizkaia Health Research Institute, Cell Therapy, Stem Cells and Tissues Group, Barakaldo, Spain

  https://orcid.org/0000-0002-8738-2077

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• Lucette van der Westerlaken,

  Roles Resources, Writing – review & editing

  Affiliation Department of Gynaecology, Leiden University Medical Center, Leiden, The Netherlands

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• Hailiang Mei,

  Roles Conceptualization, Formal analysis, Project administration, Software, Writing – review & editing

  Affiliation Sequencing Analysis Support Core, Department of Biomedical Data Sciences, Leiden University Medical Center, Leiden, The Netherlands

  https://orcid.org/0000-0003-1781-5508

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• Susana M. Chuva de Sousa Lopes

  Roles Conceptualization, Funding acquisition, Project administration, Resources, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: lopes@lumc.nl

  Affiliations Department of Anatomy and Embryology, Leiden University Medical Center, Leiden, The Netherlands, Department for Reproductive Medicine, Ghent University Hospital, Ghent, Belgium

  https://orcid.org/0000-0003-3866-2803

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