High-throughput screening and genome-wide analyses of 44 anticancer drugs in the 1000 Genomes cell lines reveals an association of the NQO1 gene with the response of multiple anticancer drugs

• Farida S. Akhtari,

  Roles Data curation, Formal analysis, Software, Visualization, Writing – original draft, Writing – review & editing

  Affiliations Department of Biological Sciences, North Carolina State University, Raleigh, North Carolina, United States of America, Bioinformatics Research Center, North Carolina State University, Raleigh, North Carolina, United States of America

  https://orcid.org/0000-0002-1089-4488

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• Adrian J. Green,

  Roles Data curation, Formal analysis, Visualization, Writing – original draft, Writing – review & editing

  Affiliations Department of Biological Sciences, North Carolina State University, Raleigh, North Carolina, United States of America, Bioinformatics Research Center, North Carolina State University, Raleigh, North Carolina, United States of America

  https://orcid.org/0000-0001-9429-1838

  ⨯
• George W. Small,

  Roles Data curation, Writing – original draft, Writing – review & editing

  Affiliation Pharmacotherapy and Experimental Therapeutics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America

  https://orcid.org/0000-0002-7585-7258

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• Tammy M. Havener,

  Roles Data curation, Methodology

  Affiliation Pharmacotherapy and Experimental Therapeutics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America

  https://orcid.org/0000-0002-4613-0498

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• John S. House,

  Roles Validation, Visualization, Writing – review & editing

  Affiliation Biostatistics and Computational Biology Branch, National Institute of Environmental Health Sciences, Durham, North Carolina, United States of America

  https://orcid.org/0000-0002-8447-7871

  ⨯
• Kyle R. Roell,

  Roles Data curation, Software, Writing – review & editing

  Affiliation Bioinformatics Research Center, North Carolina State University, Raleigh, North Carolina, United States of America

  https://orcid.org/0000-0001-7491-6095

  ⨯
• David M. Reif,

  Roles Funding acquisition, Project administration, Supervision, Writing – review & editing

  Affiliations Department of Biological Sciences, North Carolina State University, Raleigh, North Carolina, United States of America, Bioinformatics Research Center, North Carolina State University, Raleigh, North Carolina, United States of America

  https://orcid.org/0000-0001-7815-6767

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• Howard L. McLeod,

  Roles Conceptualization, Funding acquisition, Writing – review & editing

  Affiliations Geriatric Oncology Consortium, Tampa, Florida, United States of America, USF Taneja College of Pharmacy, Tampa, Florida, United States of America

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• Timothy Wiltshire,

  Roles Conceptualization, Funding acquisition, Project administration, Supervision, Writing – review & editing

  Affiliations Pharmacotherapy and Experimental Therapeutics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America, Center for Pharmacogenomics and Individualized Therapy, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America

  https://orcid.org/0000-0001-5960-4034

  ⨯
• Alison A. Motsinger-Reif

  Roles Conceptualization, Funding acquisition, Project administration, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: alison.motsinger-reif@nih.gov

  Affiliation Biostatistics and Computational Biology Branch, National Institute of Environmental Health Sciences, Durham, North Carolina, United States of America

  https://orcid.org/0000-0003-1346-2493

  ⨯