The blood flow-klf6a-tagln2 axis drives vessel pruning in zebrafish by regulating endothelial cell rearrangement and actin cytoskeleton dynamics

• Lin Wen ,

  Contributed equally to this work with: Lin Wen, Tao Zhang, Jinxuan Wang

  Roles Data curation, Investigation, Methodology, Validation, Writing – original draft

  Affiliations Key Laboratory for Biorheological Science and Technology of Ministry of Education, Bioengineering College of Chongqing University, Chongqing, China, State and Local Joint Engineering Laboratory for Vascular Implants, Bioengineering College of Chongqing University, Chongqing, China

  ⨯
• Tao Zhang ,

  Contributed equally to this work with: Lin Wen, Tao Zhang, Jinxuan Wang

  Roles Funding acquisition

  Affiliations Key Laboratory for Biorheological Science and Technology of Ministry of Education, Bioengineering College of Chongqing University, Chongqing, China, State and Local Joint Engineering Laboratory for Vascular Implants, Bioengineering College of Chongqing University, Chongqing, China

  https://orcid.org/0000-0001-6031-2143

  ⨯
• Jinxuan Wang ,

  Contributed equally to this work with: Lin Wen, Tao Zhang, Jinxuan Wang

  Roles Data curation

  Affiliations Key Laboratory for Biorheological Science and Technology of Ministry of Education, Bioengineering College of Chongqing University, Chongqing, China, State and Local Joint Engineering Laboratory for Vascular Implants, Bioengineering College of Chongqing University, Chongqing, China

  ⨯
• Xuepu Jin,

  Roles Data curation

  Affiliations Key Laboratory for Biorheological Science and Technology of Ministry of Education, Bioengineering College of Chongqing University, Chongqing, China, State and Local Joint Engineering Laboratory for Vascular Implants, Bioengineering College of Chongqing University, Chongqing, China

  ⨯
• Muhammad Abdul Rouf,

  Roles Methodology

  Affiliations Key Laboratory for Biorheological Science and Technology of Ministry of Education, Bioengineering College of Chongqing University, Chongqing, China, State and Local Joint Engineering Laboratory for Vascular Implants, Bioengineering College of Chongqing University, Chongqing, China

  https://orcid.org/0000-0002-4076-2291

  ⨯
• Desha Luo,

  Roles Data curation

  Affiliations Key Laboratory for Biorheological Science and Technology of Ministry of Education, Bioengineering College of Chongqing University, Chongqing, China, State and Local Joint Engineering Laboratory for Vascular Implants, Bioengineering College of Chongqing University, Chongqing, China

  ⨯
• Yuan Zhu,

  Roles Methodology

  Affiliations Key Laboratory for Biorheological Science and Technology of Ministry of Education, Bioengineering College of Chongqing University, Chongqing, China, State and Local Joint Engineering Laboratory for Vascular Implants, Bioengineering College of Chongqing University, Chongqing, China

  ⨯
• Daoxi Lei,

  Roles Methodology

  Affiliations Key Laboratory for Biorheological Science and Technology of Ministry of Education, Bioengineering College of Chongqing University, Chongqing, China, State and Local Joint Engineering Laboratory for Vascular Implants, Bioengineering College of Chongqing University, Chongqing, China

  https://orcid.org/0000-0001-6477-0088

  ⨯
• Hans Gregersen,

  Roles Writing – review & editing

  Affiliations Key Laboratory for Biorheological Science and Technology of Ministry of Education, Bioengineering College of Chongqing University, Chongqing, China, State and Local Joint Engineering Laboratory for Vascular Implants, Bioengineering College of Chongqing University, Chongqing, China

  ⨯
• Yeqi Wang ,

  Roles Funding acquisition, Writing – original draft

  * E-mail: yeqi.wang@cqu.edu.cn (YQW); wanggx@cqu.edu.cn (GXW)

  Affiliations Key Laboratory for Biorheological Science and Technology of Ministry of Education, Bioengineering College of Chongqing University, Chongqing, China, State and Local Joint Engineering Laboratory for Vascular Implants, Bioengineering College of Chongqing University, Chongqing, China

  https://orcid.org/0000-0003-2881-4607

  ⨯
• Guixue Wang

  Roles Conceptualization, Funding acquisition, Resources, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: yeqi.wang@cqu.edu.cn (YQW); wanggx@cqu.edu.cn (GXW)

  Affiliations Key Laboratory for Biorheological Science and Technology of Ministry of Education, Bioengineering College of Chongqing University, Chongqing, China, State and Local Joint Engineering Laboratory for Vascular Implants, Bioengineering College of Chongqing University, Chongqing, China

  https://orcid.org/0000-0003-1883-8023

  ⨯