Aging-related upregulation of the homeobox gene caudal represses intestinal stem cell differentiation in Drosophila

• Kun Wu ,

  Contributed equally to this work with: Kun Wu, Yiming Tang, Qiaoqiao Zhang

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Software, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Key Laboratory of Gene Engineering of the Ministry of Education, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-sen University, Guangzhou, Guangdong, China

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• Yiming Tang ,

  Contributed equally to this work with: Kun Wu, Yiming Tang, Qiaoqiao Zhang

  Roles Data curation, Formal analysis, Investigation, Methodology, Project administration, Software, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Key Laboratory of Gene Engineering of the Ministry of Education, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-sen University, Guangzhou, Guangdong, China

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• Qiaoqiao Zhang ,

  Contributed equally to this work with: Kun Wu, Yiming Tang, Qiaoqiao Zhang

  Roles Data curation, Investigation, Methodology, Validation

  Affiliation Key Laboratory of Gene Engineering of the Ministry of Education, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-sen University, Guangzhou, Guangdong, China

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• Zhangpeng Zhuo,

  Roles Data curation, Investigation, Methodology, Software, Validation, Visualization

  Affiliation Key Laboratory of Gene Engineering of the Ministry of Education, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-sen University, Guangzhou, Guangdong, China

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• Xiao Sheng,

  Roles Writing – review & editing

  Affiliation Laboratory for Aging and Stem Cell Research, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, Chengdu, Sichuan, China

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• Jingping Huang,

  Roles Data curation

  Affiliation Key Laboratory of Gene Engineering of the Ministry of Education, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-sen University, Guangzhou, Guangdong, China

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• Jie’er Ye,

  Roles Data curation, Validation

  Affiliation Key Laboratory of Gene Engineering of the Ministry of Education, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-sen University, Guangzhou, Guangdong, China

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• Xiaorong Li,

  Roles Data curation

  Affiliation Key Laboratory of Gene Engineering of the Ministry of Education, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-sen University, Guangzhou, Guangdong, China

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• Zhiming Liu,

  Roles Writing – original draft, Writing – review & editing

  Affiliation Laboratory for Aging and Stem Cell Research, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, Chengdu, Sichuan, China

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• Haiyang Chen

  Roles Conceptualization, Funding acquisition, Methodology, Project administration, Resources, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: chenhy82@scu.edu.cn

  Affiliation Laboratory for Aging and Stem Cell Research, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, Chengdu, Sichuan, China

  https://orcid.org/0000-0001-8305-4060

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