Ribosomal DNA promoter recognition is determined in vivo by cooperation between UBTF1 and SL1 and is compromised in the UBTF-E210K neuroregression syndrome

• Michel G. Tremblay ,

  Roles Formal analysis, Investigation, Methodology, Resources, Supervision, Validation, Visualization, Writing – review & editing

  ¶‡ These authors share first authorship on this work

  Affiliation Laboratory of Growth and Development, St-Patrick Research Group in Basic Oncology, Cancer Division of the Quebec University Hospital Research Centre, Québec, Canada

  https://orcid.org/0000-0003-2545-3682

  ⨯
• Dany S. Sibai ,

  Roles Formal analysis, Investigation

  ¶‡ These authors share first authorship on this work

  Affiliations Laboratory of Growth and Development, St-Patrick Research Group in Basic Oncology, Cancer Division of the Quebec University Hospital Research Centre, Québec, Canada, Department of Molecular Biology, Medical Biochemistry and Pathology, Faculty of Medicine, Laval University, Québec, Canada

  https://orcid.org/0000-0001-8417-1111

  ⨯
• Melissa Valère,

  Roles Investigation

  Affiliations Laboratory of Growth and Development, St-Patrick Research Group in Basic Oncology, Cancer Division of the Quebec University Hospital Research Centre, Québec, Canada, Department of Molecular Biology, Medical Biochemistry and Pathology, Faculty of Medicine, Laval University, Québec, Canada

  https://orcid.org/0000-0002-8704-3809

  ⨯
• Jean-Clément Mars,

  Roles Investigation

  Current address: IRIC, Université de Montréal, Montréal, Québec, Canada

  Affiliations Laboratory of Growth and Development, St-Patrick Research Group in Basic Oncology, Cancer Division of the Quebec University Hospital Research Centre, Québec, Canada, Department of Molecular Biology, Medical Biochemistry and Pathology, Faculty of Medicine, Laval University, Québec, Canada

  https://orcid.org/0000-0001-8904-9502

  ⨯
• Frédéric Lessard,

  Roles Investigation, Methodology, Supervision, Writing – review & editing

  Affiliation Laboratory of Growth and Development, St-Patrick Research Group in Basic Oncology, Cancer Division of the Quebec University Hospital Research Centre, Québec, Canada

  https://orcid.org/0000-0002-1724-7267

  ⨯
• Roderick T. Hori,

  Roles Funding acquisition, Methodology

  Affiliation Departments of Microbiology, Immunology and Biochemistry

  ⨯
• Mohammad Moshahid Khan,

  Roles Funding acquisition, Methodology, Resources

  Affiliation Departments of Neurology and Anatomy & Neurobiology, University of Tennessee Health Science Center, Memphis, Tennessee, United States of America

  https://orcid.org/0000-0003-4679-294X

  ⨯
• Victor Y. Stefanovsky,

  Roles Investigation

  Affiliation Laboratory of Growth and Development, St-Patrick Research Group in Basic Oncology, Cancer Division of the Quebec University Hospital Research Centre, Québec, Canada

  ⨯
• Mark S. LeDoux,

  Roles Funding acquisition, Writing – review & editing

  Affiliation Department of Psychology, University of Memphis, Memphis TN and Veracity Neuroscience LLC, Memphis, Tennessee, United States of America

  ⨯
• Tom Moss

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: Tom.Moss@crhdq.ulaval.ca

  Affiliations Laboratory of Growth and Development, St-Patrick Research Group in Basic Oncology, Cancer Division of the Quebec University Hospital Research Centre, Québec, Canada, Department of Molecular Biology, Medical Biochemistry and Pathology, Faculty of Medicine, Laval University, Québec, Canada

  https://orcid.org/0000-0003-2047-4783

  ⨯