Prmt5 promotes vascular morphogenesis independently of its methyltransferase activity

Aurélie Quillien; Guerric Gilbert; Manon Boulet; Séverine Ethuin; Lucas Waltzer; Laurence Vandel

doi:10.1371/journal.pgen.1009641

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Open Access

Peer-reviewed

Research Article

Prmt5 promotes vascular morphogenesis independently of its methyltransferase activity

Aurélie Quillien ,

Roles Conceptualization, Formal analysis, Investigation, Validation, Writing – original draft, Writing – review & editing

* E-mail: aurelie.quillien@gmail.com (AQ); laurence.vandel@uca.fr (LV)

Affiliations Centre de Biologie du Développement (CBD), Centre de Biologie Intégrative (CBI), Université de Toulouse, CNRS, UPS, Toulouse, France, RESTORE, INSERM UMR1301, CNRS UMR5070, Université Paul Sabatier, Université de Toulouse, Toulouse, France

https://orcid.org/0000-0002-4814-1895

⨯
Guerric Gilbert,

Roles Investigation, Methodology

Affiliation Université Clermont Auvergne, CNRS, INSERM, iGReD, Clermont-Ferrand, France

https://orcid.org/0000-0002-6998-4058

⨯
Manon Boulet,

Roles Investigation, Validation

Affiliations Centre de Biologie du Développement (CBD), Centre de Biologie Intégrative (CBI), Université de Toulouse, CNRS, UPS, Toulouse, France, Université Clermont Auvergne, CNRS, INSERM, iGReD, Clermont-Ferrand, France

https://orcid.org/0000-0003-1308-3303

⨯
Séverine Ethuin,

Roles Investigation, Validation

Affiliation Centre de Biologie du Développement (CBD), Centre de Biologie Intégrative (CBI), Université de Toulouse, CNRS, UPS, Toulouse, France
⨯
Lucas Waltzer,

Roles Formal analysis, Funding acquisition, Resources, Writing – review & editing

Affiliation Université Clermont Auvergne, CNRS, INSERM, iGReD, Clermont-Ferrand, France

https://orcid.org/0000-0002-5361-727X

⨯
Laurence Vandel

Roles Conceptualization, Formal analysis, Funding acquisition, Project administration, Supervision, Writing – original draft, Writing – review & editing

* E-mail: aurelie.quillien@gmail.com (AQ); laurence.vandel@uca.fr (LV)

Affiliations Centre de Biologie du Développement (CBD), Centre de Biologie Intégrative (CBI), Université de Toulouse, CNRS, UPS, Toulouse, France, Université Clermont Auvergne, CNRS, INSERM, iGReD, Clermont-Ferrand, France

https://orcid.org/0000-0002-3692-2942

⨯

Prmt5 promotes vascular morphogenesis independently of its methyltransferase activity

Aurélie Quillien,
Guerric Gilbert,
Manon Boulet,
Séverine Ethuin,
Lucas Waltzer,
Laurence Vandel

Published: June 21, 2021
https://doi.org/10.1371/journal.pgen.1009641

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Endothelial cells
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Chromatin
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Gene expression
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Zebrafish
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Methyltransferases
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Morphogenesis
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Blood vessels
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Morpholino
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