ANGPTL8 protein-truncating variant associated with lower serum triglycerides and risk of coronary disease

• Pyry Helkkula,

  Roles Formal analysis, Methodology, Writing – original draft, Writing – review & editing

  Affiliation Institute for Molecular Medicine Finland (FIMM), HiLIFE, University of Helsinki, Helsinki, Finland

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• Tuomo Kiiskinen,

  Roles Formal analysis, Writing – review & editing

  Affiliations Institute for Molecular Medicine Finland (FIMM), HiLIFE, University of Helsinki, Helsinki, Finland, Finnish Institute for Health and Welfare, Helsinki, Finland

  https://orcid.org/0000-0002-6306-8227

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• Aki S. Havulinna,

  Roles Formal analysis, Writing – review & editing

  Affiliations Institute for Molecular Medicine Finland (FIMM), HiLIFE, University of Helsinki, Helsinki, Finland, Finnish Institute for Health and Welfare, Helsinki, Finland

  https://orcid.org/0000-0002-4787-8959

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• Juha Karjalainen,

  Roles Formal analysis, Writing – review & editing

  Affiliations Institute for Molecular Medicine Finland (FIMM), HiLIFE, University of Helsinki, Helsinki, Finland, Analytic and Translational Genetics Unit, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, United States of America, Broad Institute of the Massachusetts Institute of Technology and Harvard University, Cambridge, Massachusetts, United States of America

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• Seppo Koskinen,

  Roles Writing – review & editing

  Affiliation Finnish Institute for Health and Welfare, Helsinki, Finland

  https://orcid.org/0000-0003-1572-1735

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• Veikko Salomaa,

  Roles Resources, Writing – review & editing

  Affiliation Finnish Institute for Health and Welfare, Helsinki, Finland

  https://orcid.org/0000-0001-7563-5324

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• Mark J. Daly,

  Roles Resources, Writing – review & editing

  Affiliations Institute for Molecular Medicine Finland (FIMM), HiLIFE, University of Helsinki, Helsinki, Finland, Analytic and Translational Genetics Unit, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, United States of America, Broad Institute of the Massachusetts Institute of Technology and Harvard University, Cambridge, Massachusetts, United States of America

  https://orcid.org/0000-0002-0949-8752

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• Aarno Palotie,

  Roles Writing – review & editing

  Affiliations Institute for Molecular Medicine Finland (FIMM), HiLIFE, University of Helsinki, Helsinki, Finland, Broad Institute of the Massachusetts Institute of Technology and Harvard University, Cambridge, Massachusetts, United States of America, Psychiatric & Neurodevelopmental Genetics Unit, Department of Psychiatry, Analytic and Translational Genetics Unit, Department of Medicine, and the Department of Neurology, Massachusetts General Hospital, Boston, Massachusetts, United States of America

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• Ida Surakka,

  Roles Conceptualization, Supervision, Writing – original draft, Writing – review & editing

  Affiliations Institute for Molecular Medicine Finland (FIMM), HiLIFE, University of Helsinki, Helsinki, Finland, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, United States of America

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• Samuli Ripatti ,

  Roles Conceptualization, Resources, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: samuli.ripatti@helsinki.fi

  Affiliations Institute for Molecular Medicine Finland (FIMM), HiLIFE, University of Helsinki, Helsinki, Finland, Broad Institute of the Massachusetts Institute of Technology and Harvard University, Cambridge, Massachusetts, United States of America, Department of Public Health, University of Helsinki, Helsinki, Finland

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• FinnGen

  ¶Membership of the FinnGen is listed in the S1 Text.

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