Reduction of WDR81 impairs autophagic clearance of aggregated proteins and cell viability in neurodegenerative phenotypes

• Xuezhao Liu ,

  Contributed equally to this work with: Xuezhao Liu, Limin Yin, Tianyou Li

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Software, Validation, Writing – original draft, Writing – review & editing

  Affiliations Department of Pharmacology, School of Basic Medical Science, Fudan University, Shanghai, China, Division of Experimental Hematology and Cancer Biology, Department of Pediatrics, Brain Tumor Center, Cincinnati Children’s Hospital Medical Center, Cincinnati, United States of America

  https://orcid.org/0000-0001-7297-1429

  ⨯
• Limin Yin ,

  Contributed equally to this work with: Xuezhao Liu, Limin Yin, Tianyou Li

  Roles Data curation, Formal analysis, Investigation, Methodology, Software, Validation, Writing – original draft, Writing – review & editing

  Affiliations Department of Pharmacology, School of Basic Medical Science, Fudan University, Shanghai, China, Shanghai Key Laboratory of Bioactive Small Molecules, Fudan University, Shanghai, China

  ⨯
• Tianyou Li ,

  Contributed equally to this work with: Xuezhao Liu, Limin Yin, Tianyou Li

  Roles Data curation, Formal analysis, Investigation, Methodology, Software, Validation, Writing – original draft, Writing – review & editing

  Affiliations Department of Pharmacology, School of Basic Medical Science, Fudan University, Shanghai, China, Shanghai Key Laboratory of Bioactive Small Molecules, Fudan University, Shanghai, China

  ⨯
• Lingxi Lin,

  Roles Investigation, Methodology, Software, Validation

  Affiliation Department of Pharmacology, School of Basic Medical Science, Fudan University, Shanghai, China

  ⨯
• Jie Zhang,

  Roles Investigation, Methodology, Software, Validation

  Affiliations Department of Pharmacology, School of Basic Medical Science, Fudan University, Shanghai, China, Shanghai Key Laboratory of Bioactive Small Molecules, Fudan University, Shanghai, China

  https://orcid.org/0000-0001-7455-0492

  ⨯
• Yang Li

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Project administration, Supervision, Validation, Writing – original draft, Writing – review & editing

  * E-mail: oceanyangli@fudan.edu.cn

  Affiliations Department of Pharmacology, School of Basic Medical Science, Fudan University, Shanghai, China, Shanghai Key Laboratory of Bioactive Small Molecules, Fudan University, Shanghai, China

  https://orcid.org/0000-0002-6286-2939

  ⨯