Cross-species identification of PIP5K1-, splicing- and ubiquitin-related pathways as potential targets for RB1-deficient cells

• Andrey A. Parkhitko ,

  Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Resources, Writing – review & editing

  * E-mail: aparkhitko@pitt.edu (AAP); perrimon@receptor.med.harvard.edu (NP)

  Affiliations Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, Massachusetts, United States of America, Aging Institute of UPMC and the University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America

  https://orcid.org/0000-0001-9852-8329

  ⨯
• Arashdeep Singh,

  Roles Formal analysis, Investigation, Writing – review & editing

  Affiliation Cancer Data Science Laboratory, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America

  https://orcid.org/0000-0001-6087-7240

  ⨯
• Sharon Hsieh,

  Roles Investigation

  Affiliation Department of Biology, Boston University, Boston, Massachusetts, United States of America

  ⨯
• Yanhui Hu,

  Roles Formal analysis, Investigation

  Affiliation Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, Massachusetts, United States of America

  https://orcid.org/0000-0003-1494-1402

  ⨯
• Richard Binari,

  Roles Investigation

  Affiliations Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, Massachusetts, United States of America, Howard Hughes Medical Institute, Boston, Massachusetts, United States of America

  https://orcid.org/0000-0001-6155-9607

  ⨯
• Christopher J. Lord,

  Roles Conceptualization, Writing – review & editing

  Affiliation CRUK Gene Function Laboratory, The Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, London, United Kingdom

  ⨯
• Sridhar Hannenhalli,

  Roles Conceptualization, Formal analysis, Writing – review & editing

  Affiliation Cancer Data Science Laboratory, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America

  ⨯
• Colm J. Ryan,

  Roles Conceptualization, Formal analysis, Investigation, Writing – review & editing

  Affiliations Systems Biology Ireland, University College Dublin, Dublin, Ireland, School of Computer Science, University College Dublin, Dublin, Ireland

  https://orcid.org/0000-0003-2750-9854

  ⨯
• Norbert Perrimon

  Roles Conceptualization, Formal analysis, Funding acquisition, Resources, Writing – review & editing

  * E-mail: aparkhitko@pitt.edu (AAP); perrimon@receptor.med.harvard.edu (NP)

  Affiliations Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, Massachusetts, United States of America, Howard Hughes Medical Institute, Boston, Massachusetts, United States of America

  https://orcid.org/0000-0001-7542-472X

  ⨯