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Open Access
Peer-reviewed
Research Article
Actionable pharmacogenetic variants in Hong Kong Chinese exome sequencing data and projected prescription impact in the Hong Kong population
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Mullin Ho Chung Yu ,
Contributed equally to this work with: Mullin Ho Chung Yu, Marcus Chun Yin Chan
Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Resources, Software, Validation, Visualization, Writing – original draft
Affiliation Department of Paediatrics and Adolescent Medicine, LKS Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong SAR, China
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Marcus Chun Yin Chan ,
Contributed equally to this work with: Mullin Ho Chung Yu, Marcus Chun Yin Chan
Roles Data curation, Formal analysis, Investigation, Methodology, Resources, Validation, Visualization, Writing – original draft
Affiliation Department of Paediatrics and Adolescent Medicine, LKS Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong SAR, China
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Claudia Ching Yan Chung,
Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Visualization, Writing – original draft
Affiliation Department of Paediatrics and Adolescent Medicine, LKS Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong SAR, China
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Andrew Wang Tat Li,
Roles Data curation, Resources
Affiliation Department of Pharmacy, Queen Mary Hospital, Pokfulam, Hong Kong SAR, China
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Chara Yin Wa Yip,
Roles Resources
Affiliation Department of Pharmacy, Queen Mary Hospital, Pokfulam, Hong Kong SAR, China
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Christopher Chun Yu Mak,
Roles Methodology
Affiliation Department of Paediatrics and Adolescent Medicine, LKS Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong SAR, China
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Jeffrey Fong Ting Chau,
Roles Methodology
Affiliation Department of Paediatrics and Adolescent Medicine, LKS Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong SAR, China
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Mianne Lee,
Roles Methodology
Affiliation Department of Paediatrics and Adolescent Medicine, LKS Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong SAR, China
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Jasmine Lee Fong Fung,
Roles Methodology
Affiliation Department of Paediatrics and Adolescent Medicine, LKS Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong SAR, China
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Mandy Ho Yin Tsang,
Roles Methodology
Affiliation Department of Paediatrics and Adolescent Medicine, LKS Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong SAR, China
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Joshua Chun Ki Chan,
Roles Methodology
Affiliation Department of Paediatrics and Adolescent Medicine, LKS Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong SAR, China
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Wilfred Hing Sang Wong,
Roles Formal analysis, Resources, Software
Affiliation Department of Paediatrics and Adolescent Medicine, LKS Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong SAR, China
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Jing Yang,
Roles Resources
Affiliation Department of Paediatrics and Adolescent Medicine, LKS Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong SAR, China
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William Chun Ming Chui,
Roles Resources
Affiliation Department of Pharmacy, Queen Mary Hospital, Pokfulam, Hong Kong SAR, China
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Patrick Ho Yu Chung,
Roles Funding acquisition, Resources
Affiliation Department of Surgery, LKS Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong SAR, China
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Wanling Yang,
Roles Resources
Affiliation Department of Paediatrics and Adolescent Medicine, LKS Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong SAR, China
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So Lun Lee,
Roles Resources
Affiliations Department of Paediatrics and Adolescent Medicine, Duchess of Kent Children's Hospital, Pokfulam, Hong Kong SAR, China, Department of Paediatrics and Adolescent Medicine, Queen Mary Hospital, Pokfulam, Hong Kong SAR, China
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Godfrey Chi Fung Chan,
Roles Resources
Affiliations Department of Paediatrics and Adolescent Medicine, LKS Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong SAR, China, Department of Paediatrics and Adolescent Medicine, Queen Mary Hospital, Pokfulam, Hong Kong SAR, China, Department of Paediatrics and Adolescent Medicine, The Hong Kong Children’s Hospital, Kowloon Bay, Hong Kong SAR, China
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Paul Kwong Hang Tam,
Roles Resources
Affiliations Department of Surgery, LKS Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong SAR, China, Dr Li Dak-Sum Research Centre, The University of Hong Kong–Karolinska Institutet Collaboration in Regenerative Medicine, Pokfulam, Hong Kong SAR, China
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Yu Lung Lau,
Roles Resources
Affiliations Department of Paediatrics and Adolescent Medicine, LKS Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong SAR, China, Department of Paediatrics and Adolescent Medicine, Queen Mary Hospital, Pokfulam, Hong Kong SAR, China, Department of Paediatrics and Adolescent Medicine, The Hong Kong Children’s Hospital, Kowloon Bay, Hong Kong SAR, China
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Clara Sze Man Tang ,
Roles Methodology, Project administration, Resources, Software, Validation, Writing – review & editing
* E-mail: claratang@hku.hk (CSMT); jsks@connect.hku.hk (KSY); bhychung@hku.hk (BHYC)
Affiliations Department of Surgery, LKS Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong SAR, China, Dr Li Dak-Sum Research Centre, The University of Hong Kong–Karolinska Institutet Collaboration in Regenerative Medicine, Pokfulam, Hong Kong SAR, China
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Kit San Yeung ,
Roles Formal analysis, Project administration, Supervision, Validation, Writing – review & editing
* E-mail: claratang@hku.hk (CSMT); jsks@connect.hku.hk (KSY); bhychung@hku.hk (BHYC)
Affiliation Department of Paediatrics and Adolescent Medicine, LKS Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong SAR, China
⨯ - [ ... ],
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Brian Hon Yin Chung
Roles Conceptualization, Funding acquisition, Project administration, Supervision, Writing – review & editing
* E-mail: claratang@hku.hk (CSMT); jsks@connect.hku.hk (KSY); bhychung@hku.hk (BHYC)
Affiliations Department of Paediatrics and Adolescent Medicine, LKS Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong SAR, China, Department of Paediatrics and Adolescent Medicine, Duchess of Kent Children's Hospital, Pokfulam, Hong Kong SAR, China, Department of Paediatrics and Adolescent Medicine, Queen Mary Hospital, Pokfulam, Hong Kong SAR, China, Department of Paediatrics and Adolescent Medicine, The Hong Kong Children’s Hospital, Kowloon Bay, Hong Kong SAR, China
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Actionable pharmacogenetic variants in Hong Kong Chinese exome sequencing data and projected prescription impact in the Hong Kong population
- Mullin Ho Chung Yu,
- Marcus Chun Yin Chan,
- Claudia Ching Yan Chung,
- Andrew Wang Tat Li,
- Chara Yin Wa Yip,
- Christopher Chun Yu Mak,
- Jeffrey Fong Ting Chau,
- Mianne Lee,
- Jasmine Lee Fong Fung,
- Mandy Ho Yin Tsang
- Published: February 18, 2021
- https://doi.org/10.1371/journal.pgen.1009323