Loss of endocytosis-associated RabGEF1 causes aberrant morphogenesis and altered autophagy in photoreceptors leading to retinal degeneration

• Passley Hargrove-Grimes,

  Roles Conceptualization, Formal analysis, Investigation, Methodology, Visualization, Writing – original draft, Writing – review & editing

  Affiliations Neurobiology, Neurodegeneration & Repair Laboratory, National Eye Institute, National Institutes of Health, Bethesda, Maryland, United States of America, Institute of Biomedical Sciences, George Washington University, Washington, District of Columbia, United States of America

  https://orcid.org/0000-0002-7644-0462

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• Anupam K. Mondal ,

  Contributed equally to this work with: Anupam K. Mondal, Jessica Gumerson

  Roles Data curation, Formal analysis, Software, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Neurobiology, Neurodegeneration & Repair Laboratory, National Eye Institute, National Institutes of Health, Bethesda, Maryland, United States of America

  https://orcid.org/0000-0002-3572-6392

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• Jessica Gumerson ,

  Contributed equally to this work with: Anupam K. Mondal, Jessica Gumerson

  Roles Investigation, Methodology, Validation, Visualization, Writing – review & editing

  Affiliation Neurobiology, Neurodegeneration & Repair Laboratory, National Eye Institute, National Institutes of Health, Bethesda, Maryland, United States of America

  https://orcid.org/0000-0002-4918-6008

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• Jacob Nellissery,

  Roles Methodology, Resources, Validation, Writing – review & editing

  Affiliation Neurobiology, Neurodegeneration & Repair Laboratory, National Eye Institute, National Institutes of Health, Bethesda, Maryland, United States of America

  https://orcid.org/0000-0002-1209-664X

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• Angel M. Aponte,

  Roles Methodology, Resources, Writing – review & editing

  Affiliation Proteomics Core, National Heart Lung and Blood Institute, National Institutes of Health, Bethesda, Maryland, United States of America

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• Linn Gieser,

  Roles Methodology

  Affiliation Neurobiology, Neurodegeneration & Repair Laboratory, National Eye Institute, National Institutes of Health, Bethesda, Maryland, United States of America

  ⨯
• Haohua Qian,

  Roles Formal analysis, Resources, Writing – review & editing

  Affiliation Visual Function Core, National Eye Institute, National Institutes of Health, Bethesda, Maryland, United States of America

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• Robert N. Fariss,

  Roles Methodology, Resources, Writing – review & editing

  Affiliation Biological Imaging Core, National Eye Institute, National Institutes of Health, Bethesda, Maryland, United States of America

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• Juan S. Bonifacino,

  Roles Formal analysis, Resources, Writing – review & editing

  Affiliation Neurosciences and Cellular and Structural Biology Division, Eunice Kennedy Shriver National Institute for Child Health and Development, National Institutes of Health, Bethesda, Maryland, United States of America

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• Tiansen Li,

  Roles Formal analysis, Methodology, Supervision, Writing – review & editing

  Affiliation Neurobiology, Neurodegeneration & Repair Laboratory, National Eye Institute, National Institutes of Health, Bethesda, Maryland, United States of America

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• Anand Swaroop

  Roles Conceptualization, Formal analysis, Funding acquisition, Project administration, Resources, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: swaroopa@nei.nih.gov

  Affiliation Neurobiology, Neurodegeneration & Repair Laboratory, National Eye Institute, National Institutes of Health, Bethesda, Maryland, United States of America

  https://orcid.org/0000-0002-1975-1141

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