Runx1 is a central regulator of osteogenesis for bone homeostasis by orchestrating BMP and WNT signaling pathways

• Chen-Yi Tang,

  Roles Data curation, Formal analysis, Investigation, Visualization, Writing – original draft, Writing – review & editing

  Affiliations Department of Pathology, University of Alabama at Birmingham School of Medicine, Birmingham, Alabama, United States of America, Department of Metabolism & Endocrinology, Hunan provincial Key Laboratory of Metabolic Bone Diseases, National Clinical Research Center for Metabolic Diseases, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China

  https://orcid.org/0000-0003-1780-7997

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• Mengrui Wu,

  Roles Data curation, Formal analysis, Investigation

  Affiliations Department of Pathology, University of Alabama at Birmingham School of Medicine, Birmingham, Alabama, United States of America, Institute of Genetics, Life Science College, Zhejiang University, Hangzhou, Zhejiang, People's Republic of China

  https://orcid.org/0000-0003-1059-0916

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• Dongfeng Zhao,

  Roles Data curation, Formal analysis, Investigation

  Affiliations Department of Pathology, University of Alabama at Birmingham School of Medicine, Birmingham, Alabama, United States of America, Shanghai University of Traditional Chinese Medicine, Pudong, Shanghai, China P.R

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• Diep Edwards,

  Roles Formal analysis, Visualization, Writing – original draft

  Affiliation Department of Pathology, University of Alabama at Birmingham School of Medicine, Birmingham, Alabama, United States of America

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• Abigail McVicar,

  Roles Formal analysis, Investigation, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Department of Pathology, University of Alabama at Birmingham School of Medicine, Birmingham, Alabama, United States of America

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• Yuan Luo,

  Roles Data curation, Formal analysis, Investigation

  Affiliation Department of Pathology, University of Alabama at Birmingham School of Medicine, Birmingham, Alabama, United States of America

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• Guochun Zhu,

  Roles Data curation, Formal analysis, Investigation

  Affiliation Department of Pathology, University of Alabama at Birmingham School of Medicine, Birmingham, Alabama, United States of America

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• Yongjun Wang,

  Roles Data curation, Formal analysis, Investigation

  Affiliation Shanghai University of Traditional Chinese Medicine, Pudong, Shanghai, China P.R

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• Hou-De Zhou,

  Roles Data curation, Formal analysis

  Affiliation Department of Metabolism & Endocrinology, Hunan provincial Key Laboratory of Metabolic Bone Diseases, National Clinical Research Center for Metabolic Diseases, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China

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• Wei Chen ,

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: wechen@uab.edu (WC); ypli@uab.edu (Y-PL)

  Affiliation Department of Pathology, University of Alabama at Birmingham School of Medicine, Birmingham, Alabama, United States of America

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• Yi-Ping Li

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: wechen@uab.edu (WC); ypli@uab.edu (Y-PL)

  Affiliation Department of Pathology, University of Alabama at Birmingham School of Medicine, Birmingham, Alabama, United States of America

  https://orcid.org/0000-0003-2188-6958

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