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Open Access
Peer-reviewed
Research Article
Innate immune signaling in Drosophila shifts anabolic lipid metabolism from triglyceride storage to phospholipid synthesis to support immune function
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Brittany A. Martínez,
Roles Conceptualization, Formal analysis, Investigation, Methodology, Validation, Visualization, Writing – original draft, Writing – review & editing
Affiliations Biomedical Sciences Graduate Program, University of Virginia, Charlottesville, VA, United States of America, Department of Pharmacology, University of Virginia, Charlottesville, VA, United States of America
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Rosalie G. Hoyle,
Roles Formal analysis, Investigation, Validation, Writing – review & editing
Affiliation Department of Pharmacology, University of Virginia, Charlottesville, VA, United States of America
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Scott Yeudall,
Roles Formal analysis, Investigation, Methodology, Validation, Writing – review & editing
Affiliations Department of Pharmacology, University of Virginia, Charlottesville, VA, United States of America, Medical Scientist Training Program, University of Virginia, Charlottesville, VA, United States of America
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Mitchell E. Granade,
Roles Formal analysis, Investigation, Writing – review & editing
Affiliations Biomedical Sciences Graduate Program, University of Virginia, Charlottesville, VA, United States of America, Department of Pharmacology, University of Virginia, Charlottesville, VA, United States of America
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Thurl E. Harris,
Roles Funding acquisition, Writing – review & editing
Affiliations Biomedical Sciences Graduate Program, University of Virginia, Charlottesville, VA, United States of America, Department of Pharmacology, University of Virginia, Charlottesville, VA, United States of America
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J. David Castle,
Roles Formal analysis, Investigation, Methodology, Writing – review & editing
Affiliation Department of Cell Biology, University of Virginia, Charlottesville, VA, United States of America
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Norbert Leitinger,
Roles Funding acquisition, Writing – review & editing
Affiliations Biomedical Sciences Graduate Program, University of Virginia, Charlottesville, VA, United States of America, Department of Pharmacology, University of Virginia, Charlottesville, VA, United States of America
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Michelle L. Bland
Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Methodology, Validation, Visualization, Writing – original draft, Writing – review & editing
* E-mail: mlb2eg@virginia.edu
Affiliations Biomedical Sciences Graduate Program, University of Virginia, Charlottesville, VA, United States of America, Department of Pharmacology, University of Virginia, Charlottesville, VA, United States of America
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Innate immune signaling in Drosophila shifts anabolic lipid metabolism from triglyceride storage to phospholipid synthesis to support immune function
- Brittany A. Martínez,
- Rosalie G. Hoyle,
- Scott Yeudall,
- Mitchell E. Granade,
- Thurl E. Harris,
- J. David Castle,
- Norbert Leitinger,
- Michelle L. Bland
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- Published: November 23, 2020
- https://doi.org/10.1371/journal.pgen.1009192