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Open Access
Peer-reviewed
Research Article
Loss of hepatocyte cell division leads to liver inflammation and fibrosis
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Matthew R. Dewhurst ,
Contributed equally to this work with: Matthew R. Dewhurst, Jin Rong Ow, Gözde Zafer
Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Validation, Visualization
Affiliations Institute of Molecular and Cell Biology (IMCB), A*STAR (Agency for Science, Technology and Research), Singapore, Lydia Becker Institute of Immunology and Inflammation; and Division of Neuroscience and Experimental Psychology, School of Biological Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, University of Manchester, Manchester, United Kingdom
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Jin Rong Ow ,
Contributed equally to this work with: Matthew R. Dewhurst, Jin Rong Ow, Gözde Zafer
Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Validation, Visualization, Writing – original draft, Writing – review & editing
Affiliation Institute of Molecular and Cell Biology (IMCB), A*STAR (Agency for Science, Technology and Research), Singapore
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Gözde Zafer ,
Contributed equally to this work with: Matthew R. Dewhurst, Jin Rong Ow, Gözde Zafer
Roles Data curation, Formal analysis, Investigation, Methodology, Validation, Visualization, Writing – review & editing
Affiliations Institute of Molecular and Cell Biology (IMCB), A*STAR (Agency for Science, Technology and Research), Singapore, Department of Biochemistry, National University of Singapore (NUS), Singapore
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Noémi K. M. van Hul,
Roles Data curation, Formal analysis, Investigation, Validation
Current address: Department of Biosciences and Nutrition, Karolinska Institutet, Huddinge, Sweden
Affiliation Institute of Molecular and Cell Biology (IMCB), A*STAR (Agency for Science, Technology and Research), Singapore
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Heike Wollmann,
Roles Data curation, Investigation, Methodology
Affiliation Institute of Molecular and Cell Biology (IMCB), A*STAR (Agency for Science, Technology and Research), Singapore
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Xavier Bisteau,
Roles Data curation, Investigation, Methodology
Current address: Institute of Interdisciplinary Research (IRIBHM), Université Libre de Bruxelles, Erasme Campus, Brussels, Belgium
Affiliation Institute of Molecular and Cell Biology (IMCB), A*STAR (Agency for Science, Technology and Research), Singapore
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David Brough,
Roles Funding acquisition, Investigation, Supervision, Writing – review & editing
Affiliation Lydia Becker Institute of Immunology and Inflammation; and Division of Neuroscience and Experimental Psychology, School of Biological Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, University of Manchester, Manchester, United Kingdom
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Hyungwon Choi,
Roles Formal analysis, Investigation, Methodology, Resources, Software, Supervision, Visualization, Writing – review & editing
Affiliations Institute of Molecular and Cell Biology (IMCB), A*STAR (Agency for Science, Technology and Research), Singapore, Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore
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Philipp Kaldis
Roles Conceptualization, Funding acquisition, Investigation, Project administration, Resources, Supervision, Writing – original draft, Writing – review & editing
* E-mail: philipp.kaldis@med.lu.se
¶‡ Lead Contact
Affiliations Institute of Molecular and Cell Biology (IMCB), A*STAR (Agency for Science, Technology and Research), Singapore, Department of Biochemistry, National University of Singapore (NUS), Singapore, Department of Clinical Sciences, Lund University, Clinical Research Centre (CRC), Sweden
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Loss of hepatocyte cell division leads to liver inflammation and fibrosis
- Matthew R. Dewhurst,
- Jin Rong Ow,
- Gözde Zafer,
- Noémi K. M. van Hul,
- Heike Wollmann,
- Xavier Bisteau,
- David Brough,
- Hyungwon Choi,
- Philipp Kaldis
- Published: November 4, 2020
- https://doi.org/10.1371/journal.pgen.1009084