Fine-tuning autophagy maximises lifespan and is associated with changes in mitochondrial gene expression in Drosophila

• Ivana Bjedov ,

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: i.bjedov@ucl.ac.uk (IB); l.partridge@ucl.ac.uk (LP)

  Affiliations Institute of Healthy Ageing, Research Department of Genetics, Evolution and Environment, University College London, London, United Kingdom, UCL Cancer Institute, Paul O'Gorman Building, London United Kingdom, Max Planck Institute for Biology of Ageing, Cologne, Germany

  https://orcid.org/0000-0001-5894-6016

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• Helena M. Cochemé,

  Roles Formal analysis, Investigation, Methodology, Visualization, Writing – review & editing

  Affiliations Institute of Healthy Ageing, Research Department of Genetics, Evolution and Environment, University College London, London, United Kingdom, Max Planck Institute for Biology of Ageing, Cologne, Germany, MRC London Institute of Medical Sciences, Imperial College London, Du Cane Road, London, United Kingdom

  https://orcid.org/0000-0001-8637-0042

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• Andrea Foley,

  Roles Investigation, Methodology, Validation

  Affiliations Institute of Healthy Ageing, Research Department of Genetics, Evolution and Environment, University College London, London, United Kingdom, MRC London Institute of Medical Sciences, Imperial College London, Du Cane Road, London, United Kingdom

  https://orcid.org/0000-0003-0596-5533

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• Daniela Wieser,

  Roles Conceptualization, Formal analysis, Software

  Affiliation EMBL European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, United Kingdom

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• Nathaniel S. Woodling,

  Roles Formal analysis, Investigation, Writing – review & editing

  Affiliation Institute of Healthy Ageing, Research Department of Genetics, Evolution and Environment, University College London, London, United Kingdom

  https://orcid.org/0000-0002-0298-3800

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• Jorge Iván Castillo-Quan,

  Roles Conceptualization, Formal analysis, Investigation, Methodology, Validation

  Affiliations Institute of Healthy Ageing, Research Department of Genetics, Evolution and Environment, University College London, London, United Kingdom, Max Planck Institute for Biology of Ageing, Cologne, Germany, Section on Islet Cell and Regenerative Biology, Research Division, Joslin Diabetes Center, Boston MA, United States of America, Department of Genetics and Harvard Stem Cell Institute, Harvard Medical School, Boston MA, United States of America

  https://orcid.org/0000-0002-6324-2854

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• Povilas Norvaisas,

  Roles Formal analysis

  Affiliation Institute of Structural and Molecular Biology, University College London, London, United Kingdom

  https://orcid.org/0000-0003-4790-9820

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• Celia Lujan,

  Roles Investigation

  Affiliation UCL Cancer Institute, Paul O'Gorman Building, London United Kingdom

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• Jennifer C. Regan,

  Roles Investigation

  Current address: Institute of Immunology & Infection Research, University of Edinburgh, Charlotte, Edinburgh, United Kingdom

  Affiliations Institute of Healthy Ageing, Research Department of Genetics, Evolution and Environment, University College London, London, United Kingdom, Max Planck Institute for Biology of Ageing, Cologne, Germany

  https://orcid.org/0000-0003-2164-9151

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• Janne M. Toivonen,

  Roles Conceptualization, Investigation

  Affiliations Institute of Healthy Ageing, Research Department of Genetics, Evolution and Environment, University College London, London, United Kingdom, LAGENBIO, Facultad de Veterinaria-IIS, IA2-CITA, CIBERNED, Universidad de Zaragoza, Zaragoza, Spain

  https://orcid.org/0000-0002-7243-1737

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• Michael P. Murphy,

  Roles Conceptualization

  Affiliation MRC Mitochondrial Biology Unit, the Keith Peters Building, University of Cambridge, Cambridge, United Kingdom

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• Janet Thornton,

  Roles Formal analysis

  Affiliation EMBL European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, United Kingdom

  https://orcid.org/0000-0003-0824-4096

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• Kerri J. Kinghorn,

  Roles Conceptualization, Investigation, Writing – review & editing

  Affiliation Institute of Healthy Ageing, Research Department of Genetics, Evolution and Environment, University College London, London, United Kingdom

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• Thomas P. Neufeld,

  Roles Conceptualization

  Affiliation Department of Genetics, Cell Biology and Development, University of Minnesota, 321 Church St. SE, Minneapolis, MN, United States of America

  https://orcid.org/0000-0001-5659-4811

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• Filipe Cabreiro,

  Roles Formal analysis, Writing – review & editing

  Affiliations MRC London Institute of Medical Sciences, Imperial College London, Du Cane Road, London, United Kingdom, Institute of Structural and Molecular Biology, University College London, London, United Kingdom

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•  [ ... ],
• Linda Partridge

  Roles Conceptualization, Funding acquisition, Project administration, Resources, Supervision, Validation, Writing – review & editing

  * E-mail: i.bjedov@ucl.ac.uk (IB); l.partridge@ucl.ac.uk (LP)

  Affiliations Institute of Healthy Ageing, Research Department of Genetics, Evolution and Environment, University College London, London, United Kingdom, Max Planck Institute for Biology of Ageing, Cologne, Germany

  https://orcid.org/0000-0001-9615-0094

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