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Identification of the transcription factor Miz1 as an essential regulator of diphthamide biosynthesis using a CRISPR-mediated genome-wide screen
- Jie Liu,
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Zehua Zuo,
Roles Data curation, Formal analysis, Investigation, Methodology, Resources, Validation, Visualization
Affiliation Aging Institute of University of Pittsburgh and University of Pittsburgh Medical Center, Pittsburgh, PA, United States of America
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Meijuan Zou,
Roles Data curation, Formal analysis, Investigation, Methodology, Resources, Validation, Visualization
Affiliation Aging Institute of University of Pittsburgh and University of Pittsburgh Medical Center, Pittsburgh, PA, United States of America
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Toren Finkel,
Roles Resources, Writing – review & editing
Affiliations Aging Institute of University of Pittsburgh and University of Pittsburgh Medical Center, Pittsburgh, PA, United States of America, Division of Cardiology, Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, United States of America
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Shihui Liu
Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing
* E-mail: SHL176@pitt.edu
Affiliations Aging Institute of University of Pittsburgh and University of Pittsburgh Medical Center, Pittsburgh, PA, United States of America, Division of Infectious Diseases, Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, United States of America
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https://orcid.org/0000-0001-6240-5394
Identification of the transcription factor Miz1 as an essential regulator of diphthamide biosynthesis using a CRISPR-mediated genome-wide screen
- Jie Liu,
- Zehua Zuo,
- Meijuan Zou,
- Toren Finkel,
- Shihui Liu
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- Published: October 15, 2020
- https://doi.org/10.1371/journal.pgen.1009068