Integrating comprehensive functional annotations to boost power and accuracy in gene-based association analysis

• Corbin Quick ,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Resources, Software, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: qcorbin@hsph.harvard.edu (CQ); hmkang@umich.edu (HMK)

  ¶‡ This work was primarily completed while at the University of Michigan, Ann Arbor.

  Affiliations Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA, Department of Biostatistics, Harvard T. H. Chan School of Public Health, Boston, MA, USA

  https://orcid.org/0000-0001-7199-2930

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• Xiaoquan Wen,

  Roles Resources, Software, Writing – review & editing

  Affiliation Department of Biostatistics, Harvard T. H. Chan School of Public Health, Boston, MA, USA

  https://orcid.org/0000-0001-8990-2737

  ⨯
• Gonçalo Abecasis,

  Roles Conceptualization, Investigation, Resources, Writing – review & editing

  Affiliations Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA, Regeneron Genetics Center, Regeneron Pharmaceuticals, Tarrytown, NY, USA

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• Michael Boehnke,

  Roles Conceptualization, Funding acquisition, Project administration, Resources, Supervision, Writing – review & editing

  Affiliation Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA

  https://orcid.org/0000-0002-6442-7754

  ⨯
• Hyun Min Kang

  Roles Conceptualization, Funding acquisition, Investigation, Methodology, Project administration, Resources, Software, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: qcorbin@hsph.harvard.edu (CQ); hmkang@umich.edu (HMK)

  Affiliation Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA

  https://orcid.org/0000-0002-3631-3979

  ⨯