Aldh inhibitor restores auditory function in a mouse model of human deafness

• Guang-Jie Zhu ,

  Contributed equally to this work with: Guang-Jie Zhu, Sihao Gong, Deng-Bin Ma, Tao Tao, Wei-Qi He

  Roles Data curation, Formal analysis, Investigation, Methodology, Validation, Writing – original draft

  Affiliation Department of Otorhinolaryngology, Provincial Key Discipline of the affiliated Drum Tower Hospital of Nanjing University and Model Animal Research Center, MOE Key Laboratory of Model Animal for Disease Studies, School of Medicine, Nanjing University, Nanjing, China

  ⨯
• Sihao Gong ,

  Contributed equally to this work with: Guang-Jie Zhu, Sihao Gong, Deng-Bin Ma, Tao Tao, Wei-Qi He

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Writing – original draft

  Affiliation Department of Otorhinolaryngology, Provincial Key Discipline of the affiliated Drum Tower Hospital of Nanjing University and Model Animal Research Center, MOE Key Laboratory of Model Animal for Disease Studies, School of Medicine, Nanjing University, Nanjing, China

  ⨯
• Deng-Bin Ma ,

  Contributed equally to this work with: Guang-Jie Zhu, Sihao Gong, Deng-Bin Ma, Tao Tao, Wei-Qi He

  Roles Data curation, Formal analysis, Methodology

  Affiliation Department of Otorhinolaryngology, Provincial Key Discipline of the affiliated Drum Tower Hospital of Nanjing University and Model Animal Research Center, MOE Key Laboratory of Model Animal for Disease Studies, School of Medicine, Nanjing University, Nanjing, China

  ⨯
• Tao Tao ,

  Contributed equally to this work with: Guang-Jie Zhu, Sihao Gong, Deng-Bin Ma, Tao Tao, Wei-Qi He

  Roles Data curation, Formal analysis, Investigation, Methodology, Validation

  Affiliation Department of Otorhinolaryngology, Provincial Key Discipline of the affiliated Drum Tower Hospital of Nanjing University and Model Animal Research Center, MOE Key Laboratory of Model Animal for Disease Studies, School of Medicine, Nanjing University, Nanjing, China

  http://orcid.org/0000-0003-4066-8171

  ⨯
• Wei-Qi He ,

  Contributed equally to this work with: Guang-Jie Zhu, Sihao Gong, Deng-Bin Ma, Tao Tao, Wei-Qi He

  Roles Data curation, Formal analysis, Investigation, Methodology

  Affiliations Department of Otorhinolaryngology, Provincial Key Discipline of the affiliated Drum Tower Hospital of Nanjing University and Model Animal Research Center, MOE Key Laboratory of Model Animal for Disease Studies, School of Medicine, Nanjing University, Nanjing, China, Jiangsu Key Laboratory of Neuropsychiatric Diseases and Cambridge-Suda (CAM-SU) Genomic Resource Center, Medical College of Soochow University, Suzhou, China

  http://orcid.org/0000-0003-3137-8420

  ⨯
• Linqing Zhang,

  Roles Data curation, Formal analysis, Investigation, Methodology

  Affiliation Department of Otorhinolaryngology, Provincial Key Discipline of the affiliated Drum Tower Hospital of Nanjing University and Model Animal Research Center, MOE Key Laboratory of Model Animal for Disease Studies, School of Medicine, Nanjing University, Nanjing, China

  ⨯
• Fang Wang,

  Roles Formal analysis, Investigation, Methodology

  Affiliation Department of Otorhinolaryngology, Provincial Key Discipline of the affiliated Drum Tower Hospital of Nanjing University and Model Animal Research Center, MOE Key Laboratory of Model Animal for Disease Studies, School of Medicine, Nanjing University, Nanjing, China

  http://orcid.org/0000-0003-2280-3923

  ⨯
• Xiao-Yun Qian,

  Roles Conceptualization

  Affiliation Department of Otorhinolaryngology, Provincial Key Discipline of the affiliated Drum Tower Hospital of Nanjing University and Model Animal Research Center, MOE Key Laboratory of Model Animal for Disease Studies, School of Medicine, Nanjing University, Nanjing, China

  ⨯
• Han Zhou,

  Roles Data curation, Investigation

  Affiliation Department of Otorhinolaryngology, Provincial Key Discipline of the affiliated Drum Tower Hospital of Nanjing University and Model Animal Research Center, MOE Key Laboratory of Model Animal for Disease Studies, School of Medicine, Nanjing University, Nanjing, China

  ⨯
• Chi Fan,

  Roles Investigation

  Affiliation Department of Otorhinolaryngology, Provincial Key Discipline of the affiliated Drum Tower Hospital of Nanjing University and Model Animal Research Center, MOE Key Laboratory of Model Animal for Disease Studies, School of Medicine, Nanjing University, Nanjing, China

  ⨯
• Pei Wang,

  Roles Formal analysis, Investigation

  Affiliation Department of Otorhinolaryngology, Provincial Key Discipline of the affiliated Drum Tower Hospital of Nanjing University and Model Animal Research Center, MOE Key Laboratory of Model Animal for Disease Studies, School of Medicine, Nanjing University, Nanjing, China

  http://orcid.org/0000-0002-0538-7641

  ⨯
• Xin Chen,

  Roles Investigation

  Affiliation Department of Otorhinolaryngology, Provincial Key Discipline of the affiliated Drum Tower Hospital of Nanjing University and Model Animal Research Center, MOE Key Laboratory of Model Animal for Disease Studies, School of Medicine, Nanjing University, Nanjing, China

  ⨯
• Wei Zhao,

  Roles Investigation

  Affiliation Department of Otorhinolaryngology, Provincial Key Discipline of the affiliated Drum Tower Hospital of Nanjing University and Model Animal Research Center, MOE Key Laboratory of Model Animal for Disease Studies, School of Medicine, Nanjing University, Nanjing, China

  ⨯
• Jie Sun,

  Roles Investigation

  Affiliation Department of Otorhinolaryngology, Provincial Key Discipline of the affiliated Drum Tower Hospital of Nanjing University and Model Animal Research Center, MOE Key Laboratory of Model Animal for Disease Studies, School of Medicine, Nanjing University, Nanjing, China

  http://orcid.org/0000-0002-6855-9076

  ⨯
• Huaqun Chen,

  Roles Conceptualization

  Affiliation College of Life Science, Nanjing Normal University, Nanjing, China

  http://orcid.org/0000-0002-3860-5887

  ⨯
• Ye Wang,

  Roles Investigation

  Affiliation Nanjing MuCyte Biotechnology Co., Ltd., Nanjing, China

  ⨯
• Xiang Gao,

  Roles Conceptualization, Resources

  Affiliation Department of Otorhinolaryngology, Provincial Key Discipline of the affiliated Drum Tower Hospital of Nanjing University and Model Animal Research Center, MOE Key Laboratory of Model Animal for Disease Studies, School of Medicine, Nanjing University, Nanjing, China

  ⨯
• Jian Zuo,

  Roles Conceptualization, Funding acquisition, Supervision, Writing – original draft, Writing – review & editing

  Affiliation Department of Biomedical Sciences, School of Medicine, Creighton University, United States of America

  http://orcid.org/0000-0002-1448-4507

  ⨯
• Min-Sheng Zhu ,

  Roles Conceptualization, Formal analysis, Funding acquisition, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: zhums@nju.edu.cn (MSZ); xiagaogao@hotmail.com (XG); guoqiangwan@nju.edu.cn (GW)

  Affiliations Department of Otorhinolaryngology, Provincial Key Discipline of the affiliated Drum Tower Hospital of Nanjing University and Model Animal Research Center, MOE Key Laboratory of Model Animal for Disease Studies, School of Medicine, Nanjing University, Nanjing, China, Institute for Brain Sciences, Nanjing University, Nanjing, China

  http://orcid.org/0000-0003-3256-6861

  ⨯
• Xia Gao ,

  Roles Conceptualization, Funding acquisition, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: zhums@nju.edu.cn (MSZ); xiagaogao@hotmail.com (XG); guoqiangwan@nju.edu.cn (GW)

  Affiliation Department of Otorhinolaryngology, Provincial Key Discipline of the affiliated Drum Tower Hospital of Nanjing University and Model Animal Research Center, MOE Key Laboratory of Model Animal for Disease Studies, School of Medicine, Nanjing University, Nanjing, China

  ⨯
•  [ ... ],
• Guoqiang Wan

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: zhums@nju.edu.cn (MSZ); xiagaogao@hotmail.com (XG); guoqiangwan@nju.edu.cn (GW)

  Affiliations Department of Otorhinolaryngology, Provincial Key Discipline of the affiliated Drum Tower Hospital of Nanjing University and Model Animal Research Center, MOE Key Laboratory of Model Animal for Disease Studies, School of Medicine, Nanjing University, Nanjing, China, Institute for Brain Sciences, Nanjing University, Nanjing, China

  http://orcid.org/0000-0003-3841-9301

  ⨯
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