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Open Access
Peer-reviewed
Research Article
Evaluation of polygenic prediction methodology within a reference-standardized framework
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Oliver Pain ,
Roles Conceptualization, Formal analysis, Investigation, Methodology, Software, Visualization, Writing – original draft
* E-mail: oliver.pain@kcl.ac.uk
Affiliations Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology and Neuroscience, King’s College London, London, United Kingdom, NIHR Maudsley Biomedical Research Centre, South London and Maudsley NHS Trust, London, United Kingdom
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Kylie P. Glanville,
Roles Data curation, Resources, Writing – review & editing
Affiliation Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology and Neuroscience, King’s College London, London, United Kingdom
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Saskia P. Hagenaars,
Roles Data curation, Resources
Affiliation Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology and Neuroscience, King’s College London, London, United Kingdom
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Saskia Selzam,
Roles Data curation, Resources, Writing – review & editing
Affiliation Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology and Neuroscience, King’s College London, London, United Kingdom
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Anna E. Fürtjes,
Roles Data curation, Resources, Writing – review & editing
Affiliation Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology and Neuroscience, King’s College London, London, United Kingdom
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Héléna A. Gaspar,
Roles Data curation, Resources
Affiliation Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology and Neuroscience, King’s College London, London, United Kingdom
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Jonathan R. I. Coleman,
Roles Data curation, Resources, Writing – review & editing
Affiliation Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology and Neuroscience, King’s College London, London, United Kingdom
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Kaili Rimfeld,
Roles Data curation, Resources, Writing – review & editing
Affiliation Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology and Neuroscience, King’s College London, London, United Kingdom
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Gerome Breen,
Roles Data curation, Resources, Writing – review & editing
Affiliations Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology and Neuroscience, King’s College London, London, United Kingdom, NIHR Maudsley Biomedical Research Centre, South London and Maudsley NHS Trust, London, United Kingdom
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Robert Plomin,
Roles Data curation, Resources, Writing – review & editing
Affiliation Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology and Neuroscience, King’s College London, London, United Kingdom
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Lasse Folkersen,
Roles Conceptualization, Methodology, Resources, Writing – review & editing
Affiliation Institute of Biological Psychiatry, Sankt Hans Hospital, Copenhagen, Denmark
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Cathryn M. Lewis
Roles Conceptualization, Funding acquisition, Project administration, Supervision, Writing – review & editing
Affiliations Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology and Neuroscience, King’s College London, London, United Kingdom, NIHR Maudsley Biomedical Research Centre, South London and Maudsley NHS Trust, London, United Kingdom, Department of Medical and Molecular Genetics, Faculty of Life Sciences and Medicine, King’s College London, London, United Kingdom
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Evaluation of polygenic prediction methodology within a reference-standardized framework
- Oliver Pain,
- Kylie P. Glanville,
- Saskia P. Hagenaars,
- Saskia Selzam,
- Anna E. Fürtjes,
- Héléna A. Gaspar,
- Jonathan R. I. Coleman,
- Kaili Rimfeld,
- Gerome Breen,
- Robert Plomin
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- Published: May 4, 2021
- https://doi.org/10.1371/journal.pgen.1009021