Human ABCB1 with an ABCB11-like degenerate nucleotide binding site maintains transport activity by avoiding nucleotide occlusion

• Katalin Goda ,

  Contributed equally to this work with: Katalin Goda, Yaprak Dönmez-Cakil

  Roles Conceptualization, Data curation, Funding acquisition, Methodology, Project administration, Resources, Supervision, Validation, Writing – original draft, Writing – review & editing

  Affiliation Department of Biophysics and Cell Biology, Faculty of Medicine, University of Debrecen, Egyetem tér, Debrecen, Hungary

  http://orcid.org/0000-0003-2001-7400

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• Yaprak Dönmez-Cakil ,

  Contributed equally to this work with: Katalin Goda, Yaprak Dönmez-Cakil

  Roles Data curation, Formal analysis, Investigation, Methodology, Writing – original draft

  Affiliations Institute of Pharmacology, Center for Physiology and Pharmacology, Medical University of Vienna, Waehringerstrasse, Vienna, Austria, Department of Histology and Embryology, Faculty of Medicine, Maltepe University, Maltepe, Istanbul, Turkey

  http://orcid.org/0000-0002-4605-1167

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• Szabolcs Tarapcsák,

  Roles Data curation, Formal analysis, Investigation, Validation, Visualization

  Affiliations Department of Biophysics and Cell Biology, Faculty of Medicine, University of Debrecen, Egyetem tér, Debrecen, Hungary, Doctoral School of Molecular Cell and Immune Biology, University of Debrecen, Egyetem tér, Debrecen, Hungary

  http://orcid.org/0000-0001-7182-0135

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• Gábor Szalóki,

  Roles Formal analysis, Investigation

  Affiliation Department of Biophysics and Cell Biology, Faculty of Medicine, University of Debrecen, Egyetem tér, Debrecen, Hungary

  http://orcid.org/0000-0001-6190-9128

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• Dániel Szöllősi,

  Roles Formal analysis, Investigation, Visualization

  Affiliation Institute of Pharmacology, Center for Physiology and Pharmacology, Medical University of Vienna, Waehringerstrasse, Vienna, Austria

  http://orcid.org/0000-0003-4641-3065

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• Zahida Parveen,

  Roles Formal analysis, Investigation

  Affiliations Institute of Medical Chemistry, Center for Pathobiochemistry and Genetics, Medical University of Vienna, Waehringerstrasse, Vienna, Austria, Department of Biochemistry, Abdul Wali Khan University Mardan, Khyber Pakhtunkhwa, Pakistan

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• Dóra Türk,

  Roles Formal analysis, Investigation

  Affiliation Institute of Enzymology, Research Centre for Natural Sciences, Hungarian Academy of Sciences, Magyar Tudósok körútja, Budapest, Hungary

  http://orcid.org/0000-0003-1215-3453

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• Gergely Szakács,

  Roles Conceptualization, Funding acquisition, Methodology, Resources, Supervision, Writing – review & editing

  Affiliations Institute of Enzymology, Research Centre for Natural Sciences, Hungarian Academy of Sciences, Magyar Tudósok körútja, Budapest, Hungary, Institute of Cancer Research, Medical University of Vienna, Borschkegasse, Vienna, Austria

  http://orcid.org/0000-0002-9311-7827

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• Peter Chiba ,

  Roles Conceptualization, Funding acquisition, Methodology, Resources, Supervision, Writing – review & editing

  * E-mail: peter.chiba@meduniwien.ac.at (PC); thomas.stockner@meduniwien.ac.at (TS)

  Affiliation Institute of Medical Chemistry, Center for Pathobiochemistry and Genetics, Medical University of Vienna, Waehringerstrasse, Vienna, Austria

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• Thomas Stockner

  Roles Conceptualization, Data curation, Funding acquisition, Methodology, Project administration, Resources, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: peter.chiba@meduniwien.ac.at (PC); thomas.stockner@meduniwien.ac.at (TS)

  Affiliation Institute of Pharmacology, Center for Physiology and Pharmacology, Medical University of Vienna, Waehringerstrasse, Vienna, Austria

  ⨯