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Open Access
Peer-reviewed
Research Article
A Drosophila model of Pontocerebellar Hypoplasia reveals a critical role for the RNA exosome in neurons
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Derrick J. Morton ,
Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing
* E-mail: djmorto@emory.edu (DJM); acorbe2@emory.edu (AHC)
Affiliation Department of Biology, RRC 1021, Emory University, NE, Atlanta, Georgia, United States of America
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Binta Jalloh,
Roles Investigation
Affiliations Genetics and Molecular Biology Graduate Program, Emory University, NE, Atlanta, Georgia, United States of America, Department of Cell Biology, Emory University School of Medicine, Atlanta, Georgia, United States of America
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Lily Kim,
Roles Investigation
Affiliation Department of Biology, RRC 1021, Emory University, NE, Atlanta, Georgia, United States of America
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Isaac Kremsky,
Roles Formal analysis, Investigation
Affiliation Department of Biology, RRC 1021, Emory University, NE, Atlanta, Georgia, United States of America
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Rishi J. Nair,
Roles Investigation
Affiliation Department of Biology, RRC 1021, Emory University, NE, Atlanta, Georgia, United States of America
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Khuong B. Nguyen,
Roles Investigation
Affiliation Department of Biology, RRC 1021, Emory University, NE, Atlanta, Georgia, United States of America
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J. Christopher Rounds,
Roles Investigation
Affiliations Genetics and Molecular Biology Graduate Program, Emory University, NE, Atlanta, Georgia, United States of America, Department of Cell Biology, Emory University School of Medicine, Atlanta, Georgia, United States of America
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Maria C. Sterrett,
Roles Investigation
Affiliations Department of Biology, RRC 1021, Emory University, NE, Atlanta, Georgia, United States of America, Biochemistry, Cell and Developmental Biology Graduate Program, Emory University, NE, Atlanta, Georgia, United States of America
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Brianna Brown,
Roles Investigation
Affiliation Department of Cell Biology, Emory University School of Medicine, Atlanta, Georgia, United States of America
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Thalia Le,
Roles Investigation
Affiliation Department of Biology, RRC 1021, Emory University, NE, Atlanta, Georgia, United States of America
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Maya C. Karkare,
Roles Investigation
Affiliation Department of Biology, RRC 1021, Emory University, NE, Atlanta, Georgia, United States of America
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Kathryn D. McGaughey,
Roles Investigation
Affiliation Department of Biology, RRC 1021, Emory University, NE, Atlanta, Georgia, United States of America
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Shaoyi Sheng,
Roles Investigation
Affiliation Department of Biology, RRC 1021, Emory University, NE, Atlanta, Georgia, United States of America
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Sara W. Leung,
Roles Conceptualization
Affiliation Department of Biology, RRC 1021, Emory University, NE, Atlanta, Georgia, United States of America
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Milo B. Fasken,
Roles Conceptualization
Affiliation Department of Biology, RRC 1021, Emory University, NE, Atlanta, Georgia, United States of America
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Kenneth H. Moberg,
Roles Conceptualization, Funding acquisition, Methodology, Writing – review & editing
Affiliation Department of Cell Biology, Emory University School of Medicine, Atlanta, Georgia, United States of America
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Anita H. Corbett
Roles Conceptualization, Funding acquisition, Methodology, Project administration, Supervision, Writing – original draft, Writing – review & editing
* E-mail: djmorto@emory.edu (DJM); acorbe2@emory.edu (AHC)
Affiliation Department of Biology, RRC 1021, Emory University, NE, Atlanta, Georgia, United States of America
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A Drosophila model of Pontocerebellar Hypoplasia reveals a critical role for the RNA exosome in neurons
- Derrick J. Morton,
- Binta Jalloh,
- Lily Kim,
- Isaac Kremsky,
- Rishi J. Nair,
- Khuong B. Nguyen,
- J. Christopher Rounds,
- Maria C. Sterrett,
- Brianna Brown,
- Thalia Le
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- Published: July 9, 2020
- https://doi.org/10.1371/journal.pgen.1008901
- See the preprint