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Open Access
Peer-reviewed
Research Article
Elevated COUP-TFII expression in dopaminergic neurons accelerates the progression of Parkinson’s disease through mitochondrial dysfunction
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Chung-Yang Kao ,
Contributed equally to this work with: Chung-Yang Kao, Mafei Xu, Leiming Wang
Roles Conceptualization, Data curation, Formal analysis, Methodology, Writing – original draft
Affiliation Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, Texas, United States of America
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Mafei Xu ,
Contributed equally to this work with: Chung-Yang Kao, Mafei Xu, Leiming Wang
Roles Formal analysis, Methodology
Affiliation Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, Texas, United States of America
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Leiming Wang ,
Contributed equally to this work with: Chung-Yang Kao, Mafei Xu, Leiming Wang
Roles Formal analysis, Methodology
Affiliation Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, Texas, United States of America
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Shih-Chieh Lin,
Roles Formal analysis, Software
Affiliations Institute of Basic Medical Sciences, College of Medicine, National Cheng Kung University, Tainan, Taiwan, Institute of Molecular Medicine, College of Medicine, National Cheng Kung University, Tainan, Taiwan, Department of Physiology, College of Medicine, National Cheng Kung University, Tainan, Taiwan
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Hui-Ju Lee,
Roles Methodology
Affiliation Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, Texas, United States of America
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Lita Duraine,
Roles Methodology
Affiliations Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas, United States of America, Howard Hughes Medical Institute, Baylor College of Medicine, Houston, Texas, United States of America
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Hugo J. Bellen,
Roles Conceptualization, Supervision
Affiliations Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas, United States of America, Howard Hughes Medical Institute, Baylor College of Medicine, Houston, Texas, United States of America, Program in Developmental Biology, Baylor College of Medicine, Houston, Texas, United States of America, Department of Neuroscience, Baylor College of Medicine, Houston, Texas, United States of America, Jan and Dan Duncan Neurological Research Institute, Texas Children's Hospital, Houston, Texas, United States of America
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David S. Goldstein,
Roles Conceptualization, Formal analysis, Methodology
Affiliation Clinical Neurocardiology Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland, United States of America
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Sophia Y. Tsai ,
Roles Conceptualization, Supervision, Writing – review & editing
* E-mail: stsai@bcm.edu (SYT); mtsai@bcm.edu (MJT)
Affiliation Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, Texas, United States of America
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Ming-Jer Tsai
Roles Conceptualization, Supervision, Writing – review & editing
* E-mail: stsai@bcm.edu (SYT); mtsai@bcm.edu (MJT)
Affiliation Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, Texas, United States of America
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Elevated COUP-TFII expression in dopaminergic neurons accelerates the progression of Parkinson’s disease through mitochondrial dysfunction
- Chung-Yang Kao,
- Mafei Xu,
- Leiming Wang,
- Shih-Chieh Lin,
- Hui-Ju Lee,
- Lita Duraine,
- Hugo J. Bellen,
- David S. Goldstein,
- Sophia Y. Tsai,
- Ming-Jer Tsai
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- Published: June 24, 2020
- https://doi.org/10.1371/journal.pgen.1008868