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Open Access
Peer-reviewed
Research Article
In vivo modeling of metastatic human high-grade serous ovarian cancer in mice
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Olga Kim ,
Contributed equally to this work with: Olga Kim, Eun Young Park
Roles Data curation, Formal analysis, Investigation, Project administration, Validation, Writing – original draft, Writing – review & editing
Affiliation Department of Biochemistry and Molecular Biology, Indiana University Melvin and Bren Simon Comprehensive Cancer Center, Indiana University School of Medicine, Indianapolis, Indiana, United States of America
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Eun Young Park ,
Contributed equally to this work with: Olga Kim, Eun Young Park
Roles Data curation, Formal analysis, Investigation, Project administration, Validation, Writing – original draft
Affiliation Department of Biochemistry and Molecular Biology, Indiana University Melvin and Bren Simon Comprehensive Cancer Center, Indiana University School of Medicine, Indianapolis, Indiana, United States of America
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David L. Klinkebiel,
Roles Data curation, Formal analysis, Investigation
Affiliation Department of Biochemistry and Molecular Biology, Fred & Pamela Buffett Cancer Center, University of Nebraska Medical Center, Omaha, Nebraska, United States of America
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Svetlana D. Pack,
Roles Formal analysis, Investigation
Affiliation Laboratory of Pathology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America
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Yong-Hyun Shin,
Roles Investigation
Affiliation Department of Biochemistry and Molecular Biology, Indiana University Melvin and Bren Simon Comprehensive Cancer Center, Indiana University School of Medicine, Indianapolis, Indiana, United States of America
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Zied Abdullaev,
Roles Investigation
Affiliation Laboratory of Pathology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America
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Robert E. Emerson,
Roles Investigation
Affiliation Department of Pathology and Laboratory Medicine, Indiana University School of Medicine, Indianapolis, Indiana, United States of America
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Donna M. Coffey,
Roles Investigation
Affiliation Department of Pathology and Genomic Medicine, Houston Methodist and Weill Cornell Medical College, Houston, Texas, United States of America
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Sun Young Kwon,
Roles Investigation
Affiliation Department of Pathology, School of Medicine, Keimyung University, Daegu, Republic of Korea
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Chad J. Creighton,
Roles Formal analysis, Funding acquisition
Affiliation Department of Medicine, Baylor College of Medicine, Houston, Texas, United States of America
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Sanghoon Kwon,
Roles Investigation
Affiliation Research and Development Center, Bioway Inc, Seoul, Republic of Korea
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Edmund C. Chang,
Roles Investigation
Affiliation Human Genome Sequencing Center, Baylor College of Medicine, Houston, Texas, United States of America
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Theodore Chiang,
Roles Investigation
Affiliation Human Genome Sequencing Center, Baylor College of Medicine, Houston, Texas, United States of America
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Alexander N. Yatsenko,
Roles Investigation, Writing – review & editing
Affiliation Department of Obstetrics, Gynecology & Reproductive Sciences, Magee-Womens Research Institute, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America
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Jeremy Chien,
Roles Investigation
Affiliation Department of Biochemistry and Molecular Medicine, University of California, Davis, Sacramento, California, United States of America
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Dong-Joo Cheon,
Roles Writing – review & editing
Affiliation Department of Regenerative and Cancer Cell Biology, Albany Medical College, Albany, NY, United States of America
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Yang Yang-Hartwich,
Roles Writing – review & editing
Affiliation Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale School of Medicine, New Haven, Connecticut, United States of America
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Harikrishna Nakshatri,
Roles Writing – review & editing
Affiliation Department of Surgery, Indiana University Melvin and Bren Simon Comprehensive Cancer Center, Indiana University School of Medicine, Indianapolis, Indiana, United States of America
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Kenneth P. Nephew,
Roles Writing – review & editing
Affiliation Medical Sciences Program, Indiana University Melvin and Bren Simon Comprehensive Cancer Center, Indiana University School of Medicine, Bloomington, Indiana, United States of America
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Richard R. Behringer,
Roles Resources
Affiliation Departments of Genetics, University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America
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Facundo M. Fernández,
Roles Funding acquisition, Writing – review & editing
Affiliation School of Chemistry and Biochemistry, Georgia Institute of Technology, Atlanta, Georgia, United States of America
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Chi-Heum Cho,
Roles Writing – review & editing
Affiliation Department of Obstetrics and Gynecology, School of Medicine, Keimyung University, Daegu, Republic of Korea
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Barbara Vanderhyden,
Roles Resources
Affiliation Department of Cellular and Molecular Medicine, University of Ottawa, and Ottawa Hospital Research Institute, Ottawa, Ontario, Canada
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Ronny Drapkin,
Roles Resources
Affiliation Penn Ovarian Cancer Research Center, Department of Obstetrics and Gynecology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
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Robert C. Bast Jr,
Roles Writing – review & editing
Affiliation Department of Experimental Therapeutics, University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America
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Kathy D. Miller,
Roles Funding acquisition, Writing – review & editing
Affiliation Department of Medicine, Indiana University Melvin and Bren Simon Comprehensive Cancer Center, Indiana University School of Medicine Indianapolis, Indiana, United States of America
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Adam R. Karpf,
Roles Supervision, Writing – review & editing
Affiliation Eppley Institute for Cancer Research, Fred & Pamela Buffett Cancer Center, University of Nebraska Medical Center, Omaha, Nebraska, United States of America
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Jaeyeon Kim
Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Supervision, Writing – original draft, Writing – review & editing
* E-mail: jaeyeonk@iu.edu
Affiliation Department of Biochemistry and Molecular Biology, Indiana University Melvin and Bren Simon Comprehensive Cancer Center, Indiana University School of Medicine, Indianapolis, Indiana, United States of America
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In vivo modeling of metastatic human high-grade serous ovarian cancer in mice
- Olga Kim,
- Eun Young Park,
- David L. Klinkebiel,
- Svetlana D. Pack,
- Yong-Hyun Shin,
- Zied Abdullaev,
- Robert E. Emerson,
- Donna M. Coffey,
- Sun Young Kwon,
- Chad J. Creighton
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- Published: June 4, 2020
- https://doi.org/10.1371/journal.pgen.1008808