Quantitative live imaging of Venus::BMAL1 in a mouse model reveals complex dynamics of the master circadian clock regulator

• Nan Yang ,

  Contributed equally to this work with: Nan Yang, Nicola J. Smyllie

  Roles Data curation, Formal analysis, Investigation, Methodology, Writing – original draft, Writing – review & editing

  ¶‡ These authors share first authorship on this work

  Affiliations Wellcome Centre for Cell Matrix Research, University of Manchester, Manchester, United Kingdom, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, United Kingdom

  ⨯
• Nicola J. Smyllie ,

  Contributed equally to this work with: Nan Yang, Nicola J. Smyllie

  Roles Data curation, Formal analysis, Investigation, Methodology, Writing – original draft, Writing – review & editing

  ¶‡ These authors share first authorship on this work

  Affiliation Division of Neurobiology, Medical Research Council Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge, United Kingdom

  http://orcid.org/0000-0002-6324-1421

  ⨯
• Honor Morris,

  Roles Data curation, Formal analysis, Investigation, Methodology, Writing – original draft

  Affiliations Wellcome Centre for Cell Matrix Research, University of Manchester, Manchester, United Kingdom, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, United Kingdom

  http://orcid.org/0000-0001-9801-5144

  ⨯
• Cátia F. Gonçalves,

  Roles Data curation, Formal analysis, Investigation, Methodology

  Affiliations Wellcome Centre for Cell Matrix Research, University of Manchester, Manchester, United Kingdom, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, United Kingdom

  http://orcid.org/0000-0001-5221-5458

  ⨯
• Michal Dudek,

  Roles Data curation, Formal analysis, Investigation

  Affiliations Wellcome Centre for Cell Matrix Research, University of Manchester, Manchester, United Kingdom, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, United Kingdom

  http://orcid.org/0000-0003-3152-1127

  ⨯
• Dharshika R. J. Pathiranage,

  Roles Data curation, Formal analysis, Methodology

  Affiliations Wellcome Centre for Cell Matrix Research, University of Manchester, Manchester, United Kingdom, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, United Kingdom

  http://orcid.org/0000-0003-0701-1880

  ⨯
• Johanna E. Chesham,

  Roles Data curation, Formal analysis, Investigation

  Affiliation Division of Neurobiology, Medical Research Council Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge, United Kingdom

  ⨯
• Antony Adamson,

  Roles Data curation, Investigation, Methodology, Resources

  Affiliation Faculty of Biology, Medicine and Health, University of Manchester, Manchester, United Kingdom

  http://orcid.org/0000-0002-5408-0013

  ⨯
• David G. Spiller,

  Roles Data curation, Formal analysis, Methodology, Software, Visualization

  Affiliation Faculty of Biology, Medicine and Health, University of Manchester, Manchester, United Kingdom

  ⨯
• Egor Zindy,

  Roles Data curation, Formal analysis, Methodology, Software, Visualization

  Affiliation Faculty of Biology, Medicine and Health, University of Manchester, Manchester, United Kingdom

  http://orcid.org/0000-0003-0033-0002

  ⨯
• James Bagnall,

  Roles Methodology, Resources, Software

  Affiliation Faculty of Biology, Medicine and Health, University of Manchester, Manchester, United Kingdom

  ⨯
• Neil Humphreys,

  Roles Resources, Validation

  Current Address: EMBL-Rome, Epigenetics and Neurobiology Unit, Italy.

  Affiliation Faculty of Biology, Medicine and Health, University of Manchester, Manchester, United Kingdom

  http://orcid.org/0000-0003-3210-4093

  ⨯
• Judith Hoyland,

  Roles Funding acquisition, Project administration, Resources, Supervision, Validation, Writing – review & editing

  Affiliations Faculty of Biology, Medicine and Health, University of Manchester, Manchester, United Kingdom, NIHR Manchester Musculoskeletal Biomedical Research Centre, Manchester University NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, United Kingdom

  http://orcid.org/0000-0003-4876-5208

  ⨯
• Andrew S. I. Loudon,

  Roles Funding acquisition, Writing – review & editing

  Affiliation Faculty of Biology, Medicine and Health, University of Manchester, Manchester, United Kingdom

  ⨯
• Michael H. Hastings,

  Roles Conceptualization, Funding acquisition, Investigation, Project administration, Supervision, Writing – original draft, Writing – review & editing

  Affiliation Division of Neurobiology, Medical Research Council Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge, United Kingdom

  ⨯
•  [ ... ],
• Qing-Jun Meng

  Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Project administration, Resources, Supervision, Validation, Writing – original draft, Writing – review & editing

  * E-mail: qing-jun.meng@manchester.ac.uk

  Affiliations Wellcome Centre for Cell Matrix Research, University of Manchester, Manchester, United Kingdom, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, United Kingdom

  http://orcid.org/0000-0002-9426-8336

  ⨯
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