Rare protein-altering variants in ANGPTL7 lower intraocular pressure and protect against glaucoma

• Yosuke Tanigawa,

  Roles Data curation, Formal analysis, Investigation, Methodology, Software, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Department of Biomedical Data Science, School of Medicine, Stanford University, Stanford, California, United States of America

  http://orcid.org/0000-0001-9759-157X

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• Michael Wainberg,

  Roles Writing – review & editing

  Affiliation Department of Biomedical Data Science, School of Medicine, Stanford University, Stanford, California, United States of America

  http://orcid.org/0000-0001-6061-0239

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• Juha Karjalainen,

  Roles Data curation, Formal analysis, Investigation, Writing – review & editing

  Affiliations Program in Medical and Population Genetics and Stanley Center for Psychiatric Research, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, United States of America, Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, Massachusetts, United States of America, Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland

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• Tuomo Kiiskinen,

  Roles Data curation, Formal analysis, Writing – review & editing

  Affiliations Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland, Finnish Institute for Health and Welfare, Helsinki, Finland

  http://orcid.org/0000-0002-6306-8227

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• Guhan Venkataraman,

  Roles Formal analysis, Methodology, Software

  Affiliation Department of Biomedical Data Science, School of Medicine, Stanford University, Stanford, California, United States of America

  http://orcid.org/0000-0003-0754-6631

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• Susanna Lemmelä,

  Roles Formal analysis, Writing – review & editing

  Affiliations Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland, Finnish Institute for Health and Welfare, Helsinki, Finland

  ⨯
• Joni A. Turunen,

  Roles Writing – review & editing

  Affiliations Department of Ophthalmology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland, Folkhälsan Research Center, Biomedicum Helsinki, Helsinki, Finland

  http://orcid.org/0000-0002-9569-9146

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• Robert R. Graham,

  Roles Writing – review & editing

  Affiliation Maze Therapeutics, South San Francisco, California, United States of America

  http://orcid.org/0000-0001-7151-4277

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• Aki S. Havulinna,

  Roles Formal analysis, Writing – review & editing

  Affiliations Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland, Finnish Institute for Health and Welfare, Helsinki, Finland

  http://orcid.org/0000-0002-4787-8959

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• Markus Perola,

  Roles Writing – review & editing

  Affiliation Finnish Institute for Health and Welfare, Helsinki, Finland

  http://orcid.org/0000-0003-4842-1667

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• Aarno Palotie,

  Roles Project administration, Writing – review & editing

  Affiliations Program in Medical and Population Genetics and Stanley Center for Psychiatric Research, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, United States of America, Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, Massachusetts, United States of America, Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland

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• FinnGen ,

  ¶FinnGen members are listed in S1 Text.

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• Mark J. Daly ,

  Contributed equally to this work with: Mark J. Daly, Manuel A. Rivas

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Software, Supervision, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: mark.daly@helsinki.fi (MJD); mrivas@stanford.edu (MAR)

  Affiliations Program in Medical and Population Genetics and Stanley Center for Psychiatric Research, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, United States of America, Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, Massachusetts, United States of America, Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland

  http://orcid.org/0000-0002-0949-8752

  ⨯
• Manuel A. Rivas

  Contributed equally to this work with: Mark J. Daly, Manuel A. Rivas

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Software, Supervision, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: mark.daly@helsinki.fi (MJD); mrivas@stanford.edu (MAR)

  Affiliation Department of Biomedical Data Science, School of Medicine, Stanford University, Stanford, California, United States of America

  http://orcid.org/0000-0003-1457-9925

  ⨯