The influence of rare variants in circulating metabolic biomarkers

• Fernando Riveros-Mckay,

  Roles Formal analysis, Investigation, Methodology, Validation, Visualization

  Affiliation Wellcome Sanger Institute, Cambridge, United Kingdom

  http://orcid.org/0000-0002-6671-1177

  ⨯
• Clare Oliver-Williams,

  Roles Formal analysis, Investigation, Methodology

  Affiliations MRC/BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom, Homerton College, Cambridge, United Kingdom

  http://orcid.org/0000-0002-3573-2426

  ⨯
• Savita Karthikeyan,

  Roles Formal analysis, Investigation

  Affiliation MRC/BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom

  http://orcid.org/0000-0002-4798-5746

  ⨯
• Klaudia Walter,

  Roles Data curation, Investigation, Resources

  Affiliation Wellcome Sanger Institute, Cambridge, United Kingdom

  http://orcid.org/0000-0003-4448-0301

  ⨯
• Kousik Kundu,

  Roles Data curation, Investigation, Resources

  Affiliations Wellcome Sanger Institute, Cambridge, United Kingdom, Department of Haematology, University of Cambridge, Cambridge Biomedical Campus, Cambridge, United Kingdom

  http://orcid.org/0000-0002-1019-8351

  ⨯
• Willem H. Ouwehand,

  Roles Funding acquisition, Resources

  Affiliations Wellcome Sanger Institute, Cambridge, United Kingdom, Department of Haematology, University of Cambridge, Cambridge Biomedical Campus, Cambridge, United Kingdom, NHS Blood and Transplant, Cambridge Biomedical Campus, Cambridge, United Kingdom

  http://orcid.org/0000-0002-7744-1790

  ⨯
• David Roberts,

  Roles Funding acquisition, Resources

  Affiliations The National Institute for Health Research Blood and Transplant Research Unit (NIHR BTRU) in Donor Health and Genomics, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom, NHS Blood and Transplant—Oxford Centre, Level 2, John Radcliffe Hospital, Oxford, United Kingdom, Radcliffe Department of Medicine, University of Oxford, John Radcliffe Hospital, Oxford, United Kingdom

  ⨯
• Emanuele Di Angelantonio,

  Roles Funding acquisition, Resources

  Affiliations Wellcome Sanger Institute, Cambridge, United Kingdom, MRC/BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom, The National Institute for Health Research Blood and Transplant Research Unit (NIHR BTRU) in Donor Health and Genomics, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom, British Heart Foundation Centre of Research Excellence, University of Cambridge, Cambridge, United Kingdom, National Institute for Health Research Cambridge Biomedical Research Centre, University of Cambridge and Cambridge University Hospitals, Cambridge, United Kingdom, Health Data Research UK Cambridge, Wellcome Genome Campus and University of Cambridge, Cambridge, United Kingdom

  ⨯
• Nicole Soranzo,

  Roles Resources, Supervision

  Affiliations Wellcome Sanger Institute, Cambridge, United Kingdom, Department of Haematology, University of Cambridge, Cambridge Biomedical Campus, Cambridge, United Kingdom

  ⨯
• John Danesh,

  Roles Funding acquisition, Resources

  Affiliations Wellcome Sanger Institute, Cambridge, United Kingdom, MRC/BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom, The National Institute for Health Research Blood and Transplant Research Unit (NIHR BTRU) in Donor Health and Genomics, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom, British Heart Foundation Centre of Research Excellence, University of Cambridge, Cambridge, United Kingdom, National Institute for Health Research Cambridge Biomedical Research Centre, University of Cambridge and Cambridge University Hospitals, Cambridge, United Kingdom, Health Data Research UK Cambridge, Wellcome Genome Campus and University of Cambridge, Cambridge, United Kingdom

  ⨯
• INTERVAL Study ,

  ¶Members of the INTERVAL Study are listed in the Acknowledgments.

  ⨯
• Eleanor Wheeler,

  Roles Supervision

  Affiliations Wellcome Sanger Institute, Cambridge, United Kingdom, MRC Epidemiology Unit, Wellcome Trust-MRC Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, United Kingdom

  ⨯
• Eleftheria Zeggini,

  Roles Supervision, Writing – review & editing

  Affiliations Wellcome Sanger Institute, Cambridge, United Kingdom, Institute of Translational Genomics, Helmholtz Zentrum München—German Research Center for Environmental Health, Neuherberg, Germany

  ⨯
• Adam S. Butterworth,

  Roles Funding acquisition, Resources, Supervision, Writing – review & editing

  Affiliations Wellcome Sanger Institute, Cambridge, United Kingdom, MRC/BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom, The National Institute for Health Research Blood and Transplant Research Unit (NIHR BTRU) in Donor Health and Genomics, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom, British Heart Foundation Centre of Research Excellence, University of Cambridge, Cambridge, United Kingdom, National Institute for Health Research Cambridge Biomedical Research Centre, University of Cambridge and Cambridge University Hospitals, Cambridge, United Kingdom, Health Data Research UK Cambridge, Wellcome Genome Campus and University of Cambridge, Cambridge, United Kingdom

  ⨯
• Inês Barroso

  Roles Conceptualization, Funding acquisition, Resources, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: ines.barroso@exeter.ac.uk

  Affiliations Wellcome Sanger Institute, Cambridge, United Kingdom, MRC Epidemiology Unit, Wellcome Trust-MRC Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, United Kingdom

  http://orcid.org/0000-0001-5800-4520

  ⨯